Title:
LACTOFERRIN -BASED BIOMATERIALS FOR TISSUE REGENERATION AND DRUG DELIVERY
Document Type and Number:
WIPO Patent Application WO/2011/143187
Kind Code:
A3
Abstract:
The invention provides biomatrix compositions comprising cross-linked lactoferrin, either alone or in combination with other organic or inorganic components. Also provided are methods of making and using the biomatrix compositions. As described herein, cross-linked lactoferrin biomatrix retains the bioactivities of the lactoferrin molecule. The biomatrix composition can act as a matrix for cell adhesion and growth and is particularly useful in musculoskeletal tissue regeneration. The biomatrix compositions can be pre-formed or injectable and can act as a cell, drug or protein delivery vehicle.
Inventors:
SREEDHARAN NAIR LAKSHMI (US)
Application Number:
PCT/US2011/035881
Publication Date:
March 08, 2012
Filing Date:
May 10, 2011
Export Citation:
Assignee:
UNIV CONNECTICUT (US)
SREEDHARAN NAIR LAKSHMI (US)
SREEDHARAN NAIR LAKSHMI (US)
International Classes:
A61K38/40; A61K9/06; A61K38/16; A61P19/00; A61P21/00
Foreign References:
| EP0426924A1 | 1991-05-15 | |||
| US20060229246A1 | 2006-10-12 | |||
| US20070275871A1 | 2007-11-29 |
Other References:
YOAV D. LIVNEY, CURRENT OPINION IN COLLOID & INTERFACE SCIENCE, vol. 15, 20 November 2009 (2009-11-20), pages 73 - 83, XP026896481
Attorney, Agent or Firm:
BROOK, David, E. et al. (Brook Smith & Reynolds, P.C.,530 Virginia Rd, P.o. Box 913, Concord MA, US)
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