LAG-3 ANTIBODY HAVING HIGH AFFINITY AND HIGH BIOLOGICAL ACTIVITY, AND APPLICATION THEREOF

Title:

LAG-3 ANTIBODY HAVING HIGH AFFINITY AND HIGH BIOLOGICAL ACTIVITY, AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2019/238074

Kind Code:

A1

Abstract:

Provided are an LAG-3 antibody having high affinity and high biological activity, and an application thereof. In particular, provided is a new anti-LAG-3 monoclonal antibody. The antibody is capable of binding to an LAG-3 antigen with high specificity, has high affinity and biological activity, has low immunogenicity, and is used for preparing a drug for preventing or treating LAG-3 related diseases.

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Inventors:

CAI MINGQING (CN)
PENG GUOYUAN (CN)
YU LING (CN)
FENG YUJIE (CN)
YU HAIJIA (CN)
ZHU XIANGYANG (CN)

Application Number:

PCT/CN2019/090979

Publication Date:

December 19, 2019

Filing Date:

June 12, 2019

Export Citation:

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Assignee:

HUABO BIOPHARM SHANGHAI CO LTD (CN)

International Classes:

C07K17/00; A61K39/00; A61K39/395; C07K16/28

Domestic Patent References:

WO2017219995A1	2017-12-28
WO2017037203A1	2017-03-09

Foreign References:

CN102176921A	2011-09-07
US20180127499A1	2018-05-10
CN108101991A	2018-06-01
CN106103484A	2016-11-09

Attorney, Agent or Firm:

XU & PARTNERS, LLC. (CN)

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