Title:
LANOSTEROL PRODRUG COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/137683
Kind Code:
A1
Abstract:
Disclosed are a lanosterol prodrug compound, a pharmaceutically acceptable salt and an isomer thereof, and a pharmaceutical composition comprising the lanosterol prodrug compound and the use thereof in the preparation of a drug for treating cataracts. The lanosterol prodrug compound has a better permeability than lanosterol.
Inventors:
LIU YIZHI (CN)
WANG YANDONG (CN)
LI XIAOLIN (CN)
LUO ZHI (CN)
SHEN LIANG (CN)
HOU LIJUAN (CN)
WEN XINXIN (CN)
HE HAIYING (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)
WANG YANDONG (CN)
LI XIAOLIN (CN)
LUO ZHI (CN)
SHEN LIANG (CN)
HOU LIJUAN (CN)
WEN XINXIN (CN)
HE HAIYING (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)
Application Number:
PCT/CN2018/074120
Publication Date:
August 02, 2018
Filing Date:
January 25, 2018
Export Citation:
Assignee:
ZHONGSHAN OPHTHALMIC CT SUN YAT SEN UNIV (CN)
MEDSHINE DISCOVERY INC (CN)
MEDSHINE DISCOVERY INC (CN)
International Classes:
C07J9/00; A61K9/08; A61K31/575; A61P27/12
Domestic Patent References:
| WO2016029197A1 | 2016-02-25 | |||
| WO2016029199A1 | 2016-02-25 |
Foreign References:
| CN106074568A | 2016-11-09 |
Other References:
See also references of EP 3536698A4
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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