LASER DESORPTION/IONIZATION METHOD, MASS SPECTROMETRY METHOD, SAMPLE SUPPORT BODY, AND MANUFACTURING METHOD OF SAMPLE SUPPORT BODY

WIPO Patent Application WO/2019/106961

A1

This laser desorption/ionization method involves: a first step in which a sample support body (1) is prepared that comprises a substrate (2) in which multiple through-holes (2c) are formed that open in a first surface (2a) and a second surface (2b) opposite of each other, a conductive layer which is provided on at least the first surface, and a solvent (81) which is provided in the multiple through-holes and which has low volatility in a vacuum; a second step in which the sample (S) is placed on a placement surface (6a) of a placement unit (6), and the sample support body (1) is arranged on the sample (S) such that the second surface (2b) contacts the sample; and a third step in which, in a state in which the sample (S) is arranged between the placement unit (6) and the sample support body (1), by irradiating the first surface (2a) with laser light while applying a voltage to the conductive layer, a component of the sample (S), which mixes with the solvent and moves from the second surface (2b) through the through-holes (2c) towards the first surface (2a), becomes ionized.

NAITO YASUHIDE (JP)
OHMURA TAKAYUKI (JP)
KOTANI MASAHIRO (JP)

PCT/JP2018/037453

June 06, 2019

October 05, 2018

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HAMAMATSU PHOTONICS KK (JP)

G01N27/62; G01N27/64; H01J49/04; H01J49/16

WO2017038709A1

2017-03-09

JP2003510776A	2003-03-18
JP2009080106A	2009-04-16
JP2013520655A	2013-06-06
US7695978B2	2010-04-13
JPS5129628B1	1976-08-26
US6288390B1	2001-09-11

See also references of EP 3719489A4

HASEGAWA Yoshiki et al. (JP)

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