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Title:
LATEX BEAD COMPOSITE HAVING 4-(4-METHYLPIPERAZINYL)STYRYLPYRIDINE DERIVATIVE MULTIPLY COUPLED THEREWITH, AND TARGET MATERIAL DETECTING KIT INCLUDING SAME AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2018/008897
Kind Code:
A1
Abstract:
The present invention relates to a latex bead composite having a novel 4-(4-methylpiperazinyl)styrylpyridine derivative multiply coupled therewith, a target material detecting kit including the same as an active ingredient, and a detecting method using the same. The latex bead composite having a novel 4-(4-methylpiperazinyl)styrylpyridine derivative multiply coupled therewith of the present invention has improved hydrophilic properties and thus has reduced non-specific coupling. The latex bead composite has highly favorable fluorescence brilliance, signal strength, and signal stability, and thus has the advantage in that detection can be easily performed even when a trace amount of a target material exists in a sample.

Inventors:
PARK HYUN (KR)
KIM HAK SUNG (KR)
YEO SEON-JU (KR)
CUC BUI THI (KR)
Application Number:
PCT/KR2017/006929
Publication Date:
January 11, 2018
Filing Date:
June 30, 2017
Export Citation:
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Assignee:
WONKWANG UNIV CENTER FOR INDUSTRY-ACADEMY COOPERATION (KR)
International Classes:
C07D401/14; C07D403/14; G01N33/543; G01N33/558; G01N33/58
Domestic Patent References:
WO2007084968A12007-07-26
Foreign References:
KR20150139117A2015-12-11
JP2005539243A2005-12-22
KR101740026B12017-05-26
Other References:
WU, S.: "A Bis (methylpiperazinylstyryl)phenanthroline as a Fluorescent Ligand for G-Quadruplexes", CHEMISTRY-A EUROPEAN JOURNAL, vol. 22, no. 17, 16 March 2016 (2016-03-16), pages 6037 - 6047
YEO, S. -J.: "Rapid detection of avian influenza A virus by immunochromatographic test using a novel fluorescent dye", BIOSENSORS AND BIOELECTRONICS, vol. 94, 2 April 2017 (2017-04-02), pages 677 - 685, XP029983846, DOI: doi:10.1016/j.bios.2017.03.068
Attorney, Agent or Firm:
CHOI, Kyu Whan (KR)
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