Title:
LECTIN SPECIFICALLY BOUND WITH CORE 1 O-LINKED GLYCAN DERIVED FROM HERICIUM ERINACEUS MUSHROOM, AND USE OF SAME
Document Type and Number:
WIPO Patent Application WO/2017/091030
Kind Code:
A1
Abstract:
The present invention relates to a lectin specifically bound with core 1 O-linked glycan derived from Hericium erinaceus or with a sugar chain in which sialic acid, fucose, N-acetylglucosamine, or galactose is added to a basic structure including core 1 O-linked glycan, and to a use of the same. The lectin according to the present invention can be usefully used as an active ingredient of a glycoprotein, glycopeptide, glycolipid, sugar precursor, or oligosaccharide measuring and detecting composition or kit having a sugar chain in which sialic acid, fucose, N-acetylglucosamine, or galactose is added to a basic structure including core 1 O-linked glycan, or of a cell strain, bacteria, and virus measuring or detecting composition or kit including core 1 O-linked glycan having sialic acid added therein.
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Inventors:
KIM SEONGHUN (KR)
Application Number:
PCT/KR2016/013696
Publication Date:
June 01, 2017
Filing Date:
November 25, 2016
Export Citation:
Assignee:
KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR)
International Classes:
C07K14/37; C12N15/70; G01N33/569; G01N33/574; C12R1/19
Foreign References:
| KR20150058013A | 2015-05-28 | |||
| KR20150057167A | 2015-05-28 |
Other References:
KIM ET AL.: "Carbohydrate Binding Specificity of a Core 1 O-linked Glycan-specific Lectin from the Mushroom Hericium Erinaceum", GLYCOCONJUGATE JOURNAL, vol. 32, September 2015 (2015-09-01), Croatia, pages 248 - 342, XP055386019
HASSAN ET AL.: "Mushroom Lectins: Specificity, Structure and Bioactivity Relevant to Human Disease", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 16, no. 4, 8 April 2015 (2015-04-08), pages 7802 - 7838, XP055386024
LI ET AL.: "A Novel Lectin with Antiproliferative and HIV-1 Reverse Transcriptase Inhibitory Activities from Dried Fruiting Bodies of the Monkey Head Mushroom Hericium Erinaceum", JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, vol. 2010, 2010, pages 1 - 9, XP055286281
HASSAN ET AL.: "Mushroom Lectins: Specificity, Structure and Bioactivity Relevant to Human Disease", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 16, no. 4, 8 April 2015 (2015-04-08), pages 7802 - 7838, XP055386024
LI ET AL.: "A Novel Lectin with Antiproliferative and HIV-1 Reverse Transcriptase Inhibitory Activities from Dried Fruiting Bodies of the Monkey Head Mushroom Hericium Erinaceum", JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, vol. 2010, 2010, pages 1 - 9, XP055286281
Attorney, Agent or Firm:
CHOI, Kyu Whan (KR)
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