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Title:
LEVODOPA FOR PREVENTING ADDICTION
Document Type and Number:
WIPO Patent Application WO/2024/028349
Kind Code:
A3
Abstract:
The present invention relates to levodopa for preventing the development of addiction and/or dependence to prescribed stimulants in a subject treated with stimulants. The present invention also relates to the use of a composition, pharmaceutical composition, medicament or kit comprising levodopa and a stimulant for treating diseases.

Inventors:
VIEUBLED MARGOT (FR)
MARTIN CÉLINE (FR)
SANCHEZ LOPEZ DANIEL (FR)
MINTSA M'OWONE DAVID BARTHELEMY (FR)
RATTENBACH REVITAL (FR)
Application Number:
PCT/EP2023/071331
Publication Date:
March 14, 2024
Filing Date:
August 01, 2023
Export Citation:
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Assignee:
4P PHARMA (FR)
International Classes:
A61K31/198; A61K31/137; A61K31/165; A61K31/4458; A61K45/06; A61P25/00; A61P25/30
Domestic Patent References:
WO2019091870A12019-05-16
Foreign References:
EP0204954A21986-12-17
US20180116961A12018-05-03
US20050113452A12005-05-26
Other References:
ASHOK ABHISHEKH H. ET AL: "Association of Stimulant Use With Dopaminergic Alterations in Users of Cocaine, Amphetamine, or Methamphetamine : A Systematic Review and Meta-analysis", JAMA PSYCHIATRY, vol. 74, no. 5, 1 May 2017 (2017-05-01), US, pages 511, XP093002865, ISSN: 2168-622X, DOI: 10.1001/jamapsychiatry.2017.0135
NDIDI NGWULUKA ET AL: "Levodopa delivery systems: advancements in delivery of the gold standard", EXPERT OPINION ON DRUG DELIVERY, vol. 7, no. 2, 24 February 2010 (2010-02-24), GB, pages 203 - 224, XP055282710, ISSN: 1742-5247, DOI: 10.1517/17425240903483166
YANG ET AL: "Chronic administration of methylphenidate produces neurophysiological and behavioral sensitization", BRAIN RESEARCH, ELSEVIER, AMSTERDAM, NL, vol. 1145, 31 March 2007 (2007-03-31), pages 66 - 80, XP022012033, ISSN: 0006-8993, DOI: 10.1016/J.BRAINRES.2007.01.108
Attorney, Agent or Firm:
ICOSA (FR)
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