Title:
LIGAND-DRUG CONJUGATE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/186072
Kind Code:
A1
Abstract:
The present disclosure relates to a ligand-drug conjugate of a novel structure or a pharmaceutically acceptable salt thereof. Specifically, the present disclosure provides a ligand-drug conjugate of a structural general formula of Pc-(L-D)n or a pharmaceutically acceptable salt thereof, a preparation method therefor, a pharmaceutical composition comprising the conjugate, and use thereof in treating autoimmune diseases or inflammatory diseases.
Inventors:
FU YAYUAN (CN)
CHAI XIAOJUAN (CN)
LIU LIFENG (CN)
CHEN CHANGYAN (CN)
YAN YUXI (CN)
TANG FENG (CN)
CAO ZHUOXIAO (CN)
TANG RENHONG (CN)
CHAI XIAOJUAN (CN)
LIU LIFENG (CN)
CHEN CHANGYAN (CN)
YAN YUXI (CN)
TANG FENG (CN)
CAO ZHUOXIAO (CN)
TANG RENHONG (CN)
Application Number:
PCT/CN2023/085394
Publication Date:
October 05, 2023
Filing Date:
March 31, 2023
Export Citation:
Assignee:
JIANGSU SIMCERE PHARM CO LTD (CN)
International Classes:
A61K47/68; A61P5/44; A61P29/00; A61P37/00; C07J71/00
Domestic Patent References:
| WO2010126953A1 | 2010-11-04 |
Foreign References:
| US20040043446A1 | 2004-03-04 | |||
| CN109476699A | 2019-03-15 | |||
| US20180126000A1 | 2018-05-10 |
Attorney, Agent or Firm:
INSIGHT INTELLECTUAL PROPERTY LIMITED (CN)
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