Title:
LIGAND IMMOBILIZATION METHOD
Document Type and Number:
WIPO Patent Application WO/2017/034024
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a method for strongly immobilizing a ligand on an insoluble formyl group–containing base material, wherein the method enables the production of an adsorbent, or the like, that significantly suppresses leakage of the ligand. This method for immobilizing, on an insoluble formyl group–containing base material, a ligand having an amino group and a specific affinity for a target compound is characterized by including a step for forming an imine by mixing the ligand and the insoluble formyl group–containing base material, and a step for reducing the imine using a borane complex having, as a ligand, a Lewis base with a pKa of 6.5 or lower.
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Inventors:
KONOIKE FUMINORI (JP)
HONDA TATSUYA (JP)
KARASUGI KEIICHI (JP)
HONDA TATSUYA (JP)
KARASUGI KEIICHI (JP)
Application Number:
PCT/JP2016/075000
Publication Date:
March 02, 2017
Filing Date:
August 26, 2016
Export Citation:
Assignee:
KANEKA CORP (JP)
International Classes:
G01N30/88; B01D15/08; B01J20/281; C07K1/22; C07K16/00
Domestic Patent References:
| WO2010064437A1 | 2010-06-10 |
Foreign References:
| JP2009244252A | 2009-10-22 | |||
| JP2013083447A | 2013-05-09 | |||
| JP2013506115A | 2013-02-21 |
Attorney, Agent or Firm:
UEKI, Kyuichi et al. (JP)
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