Title:
LINKED MYC-MAX SMALL MOLECULE INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2010/083404
Kind Code:
A3
Abstract:
Provided herein are compounds and compositions for interfering with the association of Myc and Max. These compounds and compositions are useful in methods for inhibiting growth or proliferation of a cell. Methods of inhibiting growth or proliferation of a cell comprise contacting the cell with an amount of a compound that interferes with Myc and Max association effective to inhibit growth or proliferation of the cell.
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Inventors:
METALLO STEVEN (US)
PROCHOWNIK EDWARD (US)
VIACAVA FOLLIS ARIELE (US)
PROCHOWNIK EDWARD (US)
VIACAVA FOLLIS ARIELE (US)
Application Number:
PCT/US2010/021183
Publication Date:
November 04, 2010
Filing Date:
January 15, 2010
Export Citation:
Assignee:
UNIV PITTSBURGH (US)
UNIV GEORGETOWN (US)
METALLO STEVEN (US)
PROCHOWNIK EDWARD (US)
VIACAVA FOLLIS ARIELE (US)
UNIV GEORGETOWN (US)
METALLO STEVEN (US)
PROCHOWNIK EDWARD (US)
VIACAVA FOLLIS ARIELE (US)
International Classes:
C07D277/14; A61K31/41; A61P35/00; C07D271/12; C07D417/12
Foreign References:
| US7026343B2 | 2006-04-11 |
Other References:
XIAOYING YIN ET AL.: "Low molecular weight inhibitors of Myc-Max interaction and function", ONCOGENE, vol. 22, no. 40, 2003, pages 6151 - 6159, XP002995346, DOI: doi:10.1038/sj.onc.1206641
Attorney, Agent or Firm:
KLARQUIST SPARKMAN, LLP (121 S.W. Salmon StreetSuite 160, Portland Oregon, US)
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