Title:
LINKER COMPOUND, DIAMOND ELECTRODE, DEVICE, METHOD FOR DETECTING PATHOGEN OR PROTEIN, AND METHOD FOR MANUFACTURING DIAMOND ELECTRODE
Document Type and Number:
WIPO Patent Application WO/2019/139009
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a technology whereby a detection object can be detected with high sensitivity. The present invention provides a linker compound represented by formula (1). (In formula (1), A represents a diazonio group, an amino group, a carboxy group, a carbonyl group, an aldehyde group, a hydroxyl group, or a nitro group, B1 and B2 may be the same or different and are each independently represented by formula (2) (in formula (2), X1 represents -NHCO- or -CH20-, X2 represents a divalent hydrocarbon group which may have a substituent, and R represents a propargyl group), and L represents an aromatic ring.)
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Inventors:
SATO TOSHINORI (JP)
MATSUBARA TERUHIKO (JP)
EINAGA YASUAKI (JP)
YAMAMOTO TAKASHI (JP)
MATSUBARA TERUHIKO (JP)
EINAGA YASUAKI (JP)
YAMAMOTO TAKASHI (JP)
Application Number:
PCT/JP2019/000248
Publication Date:
July 18, 2019
Filing Date:
January 08, 2019
Export Citation:
Assignee:
UNIV KEIO (JP)
International Classes:
C07C245/20; C12M1/34; C12Q1/04; G01N27/30; G01N27/327; G01N27/416; G01N33/547
Domestic Patent References:
| WO2016175049A1 | 2016-11-03 | |||
| WO2008100553A1 | 2008-08-21 | |||
| WO2009139683A1 | 2009-11-19 |
Other References:
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KALE, R. R., BIOORG. MED. CHEM. LETT., vol. 17, no. 9, 2007, pages 2459 - 2464, XP022015325, ISSN: 0960-894X, DOI: 10.1016/j.bmcl.2007.02.028
HATCH, D. M.: "Biotinylated Bi- and Tetra-antennary Glycoconjugates for Escherichia coli Detection", CHEMBIOCHEM, vol. 9, no. 15, 2008, pages 2433 - 2442, XP055081635, ISSN: 1439-4227, DOI: 10.1002/cbic.200800188
SAHA, A.: "Single Step Synthesis of Peripherally “Clickable” Hyperbranched Polyethers", MACROMOLECULES, vol. 42, no. 14, 28 July 2009 (2009-07-28), pages 4956 - 4959, XP055625626, ISSN: 0024-9297, DOI: 10.1021/ma900946p
INOUYE, MASAHIKO: "Molecular Recognition Abilities of a New Class of Water-Soluble Cyclophanes Capable of Encompassing a Neutral Cavity", J. AM. CHEM. SOC., vol. 121, no. 7, 1999, pages 1452 - 1458, XP055625688, ISSN: 0002-7863, DOI: 10.1021/ja9725256
KALE, R. R., BIOORG. MED. CHEM. LETT., vol. 17, no. 9, 2007, pages 2459 - 2464, XP022015325, ISSN: 0960-894X, DOI: 10.1016/j.bmcl.2007.02.028
HATCH, D. M.: "Biotinylated Bi- and Tetra-antennary Glycoconjugates for Escherichia coli Detection", CHEMBIOCHEM, vol. 9, no. 15, 2008, pages 2433 - 2442, XP055081635, ISSN: 1439-4227, DOI: 10.1002/cbic.200800188
SAHA, A.: "Single Step Synthesis of Peripherally “Clickable” Hyperbranched Polyethers", MACROMOLECULES, vol. 42, no. 14, 28 July 2009 (2009-07-28), pages 4956 - 4959, XP055625626, ISSN: 0024-9297, DOI: 10.1021/ma900946p
INOUYE, MASAHIKO: "Molecular Recognition Abilities of a New Class of Water-Soluble Cyclophanes Capable of Encompassing a Neutral Cavity", J. AM. CHEM. SOC., vol. 121, no. 7, 1999, pages 1452 - 1458, XP055625688, ISSN: 0002-7863, DOI: 10.1021/ja9725256
Attorney, Agent or Firm:
SHOBAYASHI Masayuki et al. (JP)
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