Title:
LINKER COMPOUND, LIGAND COMPLEX AND PROCESS FOR PRODUCING THEM
Document Type and Number:
WIPO Patent Application WO/2005/075453
Kind Code:
A1
Abstract:
A novel linker compound that minimizes any nonspecific hydrophobic interactions and is capable of easily regulating the length to disulfide group subjected to metal bond to thereby enable efficient formation of metal-sulfur bond; a novel ligand complex or ligand carrying substance; and a process for producing them. There is provided a linker compound comprising the structure of the general formula: (1) (wherein each of a, b, d and e independently is an integer of 0 to 6). The above X at a molecular end has an aromatic amino group and at its main chain has a structure of multi-branched structural site composed of 3 or more hydrocarbon-derived chains optionally having carbon-nitrogen bonds. The ligand complex consists of the above linker compound having a sugar molecule introduced therein.
Inventors:
SUDA YASUO
ARANO AKIO
KUSUMOTO SHOICHI
SOBEL MICHAEL
WAKAO MASAHIRO
ARANO AKIO
KUSUMOTO SHOICHI
SOBEL MICHAEL
WAKAO MASAHIRO
Application Number:
PCT/JP2005/001726
Publication Date:
August 18, 2005
Filing Date:
February 04, 2005
Export Citation:
Assignee:
JAPAN SCIENCE & TECH AGENCY (JP)
NAT UNIV CORP KAGOSHIMA (JP)
SUDA YASUO
ARANO AKIO
KUSUMOTO SHOICHI
SOBEL MICHAEL
WAKAO MASAHIRO
NAT UNIV CORP KAGOSHIMA (JP)
SUDA YASUO
ARANO AKIO
KUSUMOTO SHOICHI
SOBEL MICHAEL
WAKAO MASAHIRO
International Classes:
C07D339/04; C07H15/04; G01N33/543; (IPC1-7): C07D339/04; C07H15/04; G01N33/53; G01N37/00
Foreign References:
| US20030059865A1 | 2003-03-27 | |||
| JP2003083969A | 2003-03-19 | |||
| JP2003190568A | 2003-07-08 | |||
| JP2004157108A | 2004-06-03 |
Other References:
SUDA Y. ET AL: "Oligo-tasa no Nano Level Kino Kaiseki System no Kaihatsu.", THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH NENKAI YOSHITSU., vol. 24, 2003, pages 36, XP002991262
ARANO A. ET AL: "Ryusan Oligo-to o Shugoka Shite Koteika shita Sugar Chip no Chosei to SPR-ho eno Oyo.", THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH NENKAI YOSHISHU., vol. 24, 2003, pages 127, XP002991263
ARANO A. ET AL: "Heparin Bubun Kozo o Yusuru Cluster-Ka Oligo-tosa Rigand no Gosei to Chip Technology eno Oyo.", THE CHEMICAL SOCIETY OF JAPAN KOEN YOKOSHU., vol. 82, 2002, pages 137, XP002991264
See also references of EP 1731517A4
ARANO A. ET AL: "Ryusan Oligo-to o Shugoka Shite Koteika shita Sugar Chip no Chosei to SPR-ho eno Oyo.", THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH NENKAI YOSHISHU., vol. 24, 2003, pages 127, XP002991263
ARANO A. ET AL: "Heparin Bubun Kozo o Yusuru Cluster-Ka Oligo-tosa Rigand no Gosei to Chip Technology eno Oyo.", THE CHEMICAL SOCIETY OF JAPAN KOEN YOKOSHU., vol. 82, 2002, pages 137, XP002991264
See also references of EP 1731517A4
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (2-6, Tenjinbashi 2-chome Kita,, Kita-ku, Osaka-sh, Osaka, JP)
Download PDF: