Title:
LIPID NANOPARTICLES COMPRISING LONG-CHAIN CERAMIDE AND COMPOSITION FOR CELL DEATH COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2024/029981
Kind Code:
A1
Abstract:
A long-chain ceramide such as an exogenous C18-ceramide has very low solubility in an aqueous solution and thus has limited use, and when even used as a drug, has had poor cell delivery. In this regard, the prevent invention provides lipid nanoparticles comprising a long-chain ceramide and a preparation method therefor. Through the present invention, by delivering long-chain ceramides such as C18-ceramides to an in vivo target through lipid nanoparticles, cell death may be effectively induced according to the purpose, and utilization as a cell therapy product with high water solubility and high water dispersibility may be increased.
Inventors:
YOON TAE JONG (KR)
WON EUN JEONG (KR)
PARK SEUNG WON (KR)
KIM SANG CHUL (KR)
KIM A RA (KR)
WON EUN JEONG (KR)
PARK SEUNG WON (KR)
KIM SANG CHUL (KR)
KIM A RA (KR)
Application Number:
PCT/KR2023/011464
Publication Date:
February 08, 2024
Filing Date:
August 04, 2023
Export Citation:
Assignee:
MOOGENE MEDI CO LTD (KR)
CRODA KOREA LTD (KR)
CRODA KOREA LTD (KR)
International Classes:
A61K9/51; A61K31/164; A61P35/00
Foreign References:
| KR20200051708A | 2020-05-13 | |||
| JP2010155815A | 2010-07-15 | |||
| JP2010083802A | 2010-04-15 | |||
| US20120202871A1 | 2012-08-09 | |||
| KR101713118B1 | 2017-03-10 | |||
| KR102544632B1 | 2023-06-16 |
Attorney, Agent or Firm:
OAM PATENT & TRADEMARK LAW FIRM (KR)
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