Title:
Α-LIPOIC ACID COMPLEX
Document Type and Number:
WIPO Patent Application WO/2012/014746
Kind Code:
A1
Abstract:
Provided are an α-lipoic acid complex obtained by complexing R-α-lipoic acid or S-α-lipoic acid, R-dihdyro-α-lipoic acid or S-dihdyro-α-lipoic acid, or an alkali metal salt or an alkaline earth metal salt thereof, and a method for producing the α-lipoic acid complex.
An α-lipoic acid complex, which is stable to heat and an artificial gastric acid solution and has a high purity, can be produced by, for example, adding cyclodextrin to an aqueous solution containing, dissolved therein, R-α-lipoic acid or S-α-lipoic acid, R-dihdyro-α-lipoic acid or S-dihdyro-α-lipoic acid, or an alkali metal salt or an alkaline earth metal salt thereof and thus complexing R-α-lipoic acid or S-α-lipoic acid, R-dihdyro-α-lipoic acid or S-dihdyro-α-lipoic acid, or the alkali metal salt or the alkaline earth metal salt thereof at a high probability.
Inventors:
IKUTA, Naoko (5-5-2 KIBC654, Minatojimaminamimachi, Chuo-ku, Kobe-sh, Hyogo 47, 〒6500047, JP)
生田 直子 (〒47 兵庫県神戸市中央区港島南町５－５－２ ＫＩＢＣ６５４号 株式会社シクロケム内 Hyogo, 〒6500047, JP)
NAKATA, Daisuke (5-5-2 KIBC654, Minatojimaminamimachi, Chuo-ku, Kobe-sh, Hyogo 47, 〒6500047, JP)
生田 直子 (〒47 兵庫県神戸市中央区港島南町５－５－２ ＫＩＢＣ６５４号 株式会社シクロケム内 Hyogo, 〒6500047, JP)
NAKATA, Daisuke (5-5-2 KIBC654, Minatojimaminamimachi, Chuo-ku, Kobe-sh, Hyogo 47, 〒6500047, JP)
Application Number:
JP2011/066447
Publication Date:
February 02, 2012
Filing Date:
July 20, 2011
Export Citation:
Assignee:
CYCLOCHEM CO., LTD. (5-5-2 KIBC654, Minatojimaminamimachi Chuo-ku, Kobe-sh, Hyogo 47, 〒6500047, JP)
株式会社シクロケム (〒47 兵庫県神戸市中央区港島南町５－５－２ ＫＩＢＣ６５４号 Hyogo, 〒6500047, JP)
IKUTA, Naoko (5-5-2 KIBC654, Minatojimaminamimachi, Chuo-ku, Kobe-sh, Hyogo 47, 〒6500047, JP)
生田 直子 (〒47 兵庫県神戸市中央区港島南町５－５－２ ＫＩＢＣ６５４号 株式会社シクロケム内 Hyogo, 〒6500047, JP)
株式会社シクロケム (〒47 兵庫県神戸市中央区港島南町５－５－２ ＫＩＢＣ６５４号 Hyogo, 〒6500047, JP)
IKUTA, Naoko (5-5-2 KIBC654, Minatojimaminamimachi, Chuo-ku, Kobe-sh, Hyogo 47, 〒6500047, JP)
生田 直子 (〒47 兵庫県神戸市中央区港島南町５－５－２ ＫＩＢＣ６５４号 株式会社シクロケム内 Hyogo, 〒6500047, JP)
International Classes:
C07D339/04; A23L1/30; A61K31/385; A61P3/10
Attorney, Agent or Firm:
MOEGI PATENT OFFICE (7-7 Toranomon 2-chome, Minato-ku Tokyo, 01, 〒1050001, JP)
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