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Title:
LIPOTEICHOIC ACID-DERIVED GLYCOLIPIDS, AND COMPOSITIONS COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2011/025286
Kind Code:
A3
Abstract:
The present invention relates to lipoteichoic acid-derived glycolipids, and to pharmaceutical, food or cosmetic compositions and vaccine adjuvants comprising same. The lipoteichoic acid-derived glycolipids according to the present invention inhibit the production of inflammatory cytokines and thus have anti-inflammatory effects. Therefore, pharmaceutical, food or cosmetic compositions comprising lipoteichoic acid-derived glycolipids of the present invention can be employed for the purpose of preventing and treating inflammatory diseases. The lipoteichoic acid-derived glycolipids of the present invention can be also used as vaccine adjuvants.

Inventors:
CHUNG, Dae Kyun (1 World Meridian Apt, Uman-dong, Paldal-gu, Suwon-si, Gyeonggi-do 442-190, 442-190, KR)
정대균 (경기도 수원시 팔달구 우만동 월드메르디앙아파트, 442-190 Gyeonggi-do, 442-190, KR)
JANG, Kyoung Soon (510 29-22, Haengun-dong Gwanak-gu, Seoul 151-056, 151-056, KR)
장경순 (서울시 관악구 행운동 29-22, 510, 151-056 Seoul, 151-056, KR)
KIM, Byung Gee (1 Sampung Apt, 1685, Seocho-dong, Seocho-gu, Seoul 137-070, 137-070, KR)
김병기 (서울시 서초구 서초동 1685 삼풍아파트, 137-070 Seoul, 137-070, KR)
KIM, Han Geun (179-40, Maegyo-dong Paldal-gu, Suwon-si, Gyeonggi-do 442-844, 442-844, KR)
김한근 (경기도 수원시 팔달구 매교동 179-40, 442-844 Gyeonggi-do, 442-844, KR)
KIM, Na Ra (103 1027-24, Yeongtong 1-dong,Yeongtong-gu, Suwon-si, Gyeonggi-do 443-471, 443-471, KR)
Application Number:
KR2010/005755
Publication Date:
July 14, 2011
Filing Date:
August 26, 2010
Export Citation:
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Assignee:
RNA INC. (1 Seocheon-dong, Giheung-gu Yongin-si, Gyeonggi-do 446-906, 446-906, KR)
주식회사 알엔에이 (경기도 용인시 기흥구 서천동 1, 446-906 Gyeonggi-do, 446-906, KR)
CHUNG, Dae Kyun (1 World Meridian Apt, Uman-dong, Paldal-gu, Suwon-si, Gyeonggi-do 442-190, 442-190, KR)
정대균 (경기도 수원시 팔달구 우만동 월드메르디앙아파트, 442-190 Gyeonggi-do, 442-190, KR)
JANG, Kyoung Soon (510 29-22, Haengun-dong Gwanak-gu, Seoul 151-056, 151-056, KR)
장경순 (서울시 관악구 행운동 29-22, 510, 151-056 Seoul, 151-056, KR)
KIM, Byung Gee (1 Sampung Apt, 1685, Seocho-dong, Seocho-gu, Seoul 137-070, 137-070, KR)
김병기 (서울시 서초구 서초동 1685 삼풍아파트, 137-070 Seoul, 137-070, KR)
KIM, Han Geun (179-40, Maegyo-dong Paldal-gu, Suwon-si, Gyeonggi-do 442-844, 442-844, KR)
김한근 (경기도 수원시 팔달구 매교동 179-40, 442-844 Gyeonggi-do, 442-844, KR)
International Classes:
C07H1/06; C07H11/04; C07H15/04
Foreign References:
KR20070078107A2007-07-31
US20040137554A12004-07-15
Other References:
MORATH, S. ET AL.: 'Structure-Function Relationship of Cytokine Induction by Lipoteichoic Acid from Staphylococcus aureus' JOURNAL OF EXPERIMENTAL MEDICINE vol. 193, 05 February 2001, pages 393 - 397, XP008154433
FISCHER, W.: 'Lipoteichoic acid and lipids in the membrane of Staphylococcus aureus' MEDICAL MICROBIOLOGY AND IMMUNOLOGY vol. 183, May 1994, pages 61 - 76, XP008154435
See also references of EP 2471801A2
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (5th Floor, BYC Bldg. 648-1,Yeoksam-dong, Gangnam-gu, Seoul 135-080, 135-080, KR)
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Claims: