Title:
LIQUID CHROMATOGRAPH MASS SPECTROMETRY DEVICE
Document Type and Number:
WIPO Patent Application WO/2013/150685
Kind Code:
A1
Abstract:
To provide a liquid chromatograph mass spectrometry device in which deposition of matter such as non-volatile salts, metal ions, and polymers on the tip of the spray nozzle part is prevented, and highly accurate measurement is possible, irrespective of the presence or absence of a channel and column for desalting. Provided is a liquid chromatograph mass spectrometry device provided with: an ejection unit (1) for ejecting the sample solution supplied from the liquid chromatograph towards the liquid discharge unit (4) or the sample introduction unit (31) of the mass spectrometer (3); and an articulated robot (2) for positioning the ejection unit (1) so as to be capable of changing between the position of ejection towards the liquid discharge unit (4) and the position of ejection towards the sample introduction unit (31).
Inventors:
NATSUME TORU (JP)
ARAI TERUYASU (JP)
ARAI TERUYASU (JP)
Application Number:
PCT/JP2012/082616
Publication Date:
October 10, 2013
Filing Date:
December 17, 2012
Export Citation:
Assignee:
NAT INST OF ADVANCED IND SCIEN (JP)
NIKKYO TECHNOS CO LTD (JP)
NIKKYO TECHNOS CO LTD (JP)
International Classes:
G01N27/62; G01N30/72
Foreign References:
| JP2011237392A | 2011-11-24 | |||
| JP2005259477A | 2005-09-22 | |||
| JP2011007690A | 2011-01-13 | |||
| JP2011133245A | 2011-07-07 |
Other References:
BONNEIL,E. ET AL.: "Multiplex multidimensional nanoLC-MS system for targeted proteomic analyses", ELECTROPHORESIS, vol. 26, no. ISSUE, 15 December 2005 (2005-12-15), pages 4575 - 4589
SURUGAYA,N. ET AL.: "Automated Gravimetric Sample Pretreatment Using an Industrial Robot for the High-Precision Determination of Plutonium by Isotope Dilution Mass Spectrometry", ANALYTICAL SCIENCES, vol. 24, no. 6, 10 June 2008 (2008-06-10), pages 739 - 744
YIN,H. ET AL.: "Microfluidic Chip for Peptide Analysis with an Integrated HPLC Column, Sample Enrichment Column, and Nanoelectrospray Tip", ANALYTICAL CHEMISTRY, vol. 77, no. 2, 9 December 2004 (2004-12-09), pages 527 - 533, XP002553514, DOI: doi:10.1021/ac049068d
SURUGAYA,N. ET AL.: "Automated Gravimetric Sample Pretreatment Using an Industrial Robot for the High-Precision Determination of Plutonium by Isotope Dilution Mass Spectrometry", ANALYTICAL SCIENCES, vol. 24, no. 6, 10 June 2008 (2008-06-10), pages 739 - 744
YIN,H. ET AL.: "Microfluidic Chip for Peptide Analysis with an Integrated HPLC Column, Sample Enrichment Column, and Nanoelectrospray Tip", ANALYTICAL CHEMISTRY, vol. 77, no. 2, 9 December 2004 (2004-12-09), pages 527 - 533, XP002553514, DOI: doi:10.1021/ac049068d
Attorney, Agent or Firm:
WATANABE Kaoru et al. (JP)
Kaoru Watanabe (JP)
Kaoru Watanabe (JP)
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