Title:
LIQUID CHROMATOGRAPH AND LIQUID SAMPLE ANALYSIS METHOD
Document Type and Number:
WIPO Patent Application WO/2023/007808
Kind Code:
A1
Abstract:
Provided are a liquid chromatograph and a liquid sample analysis method by which the separation and resolution of each component as well as the measurement precision can be improved while realizing cost reduction and miniaturization of a device. Provided is a liquid sample analysis device (HPLC device) that comprises one pump, a selector valve, a column (HPLC column), a first flow channel, a second flow channel, an air-introduction passage, a detector, and a control unit. The control unit controls the pump and selector valve, can switch between introduction of an eluate and introduction of a liquid sample into a first flow channel, introduces air bubbles between the eluate and the liquid sample from an air-introduction passage, and generates an air-segmented liquid sample in a first fluid. Furthermore, the control unit controls the pump and selector valve to cause the air-segmented liquid sample to flow into the second flow channel from the first flow channel and dissolve, in the eluate and/or the liquid sample, the air bubbles passing through the second flow channel.
Inventors:
ABE RYOJI (JP)
OWADA TATSUSHI (JP)
SUZUKI SHINJI (JP)
OWADA TATSUSHI (JP)
SUZUKI SHINJI (JP)
Application Number:
PCT/JP2022/009890
Publication Date:
February 02, 2023
Filing Date:
March 08, 2022
Export Citation:
Assignee:
USHIO ELECTRIC INC (JP)
International Classes:
G01N30/26; G01N30/32
Foreign References:
| JPS5674652A | 1981-06-20 | |||
| JP5114471B2 | 2013-01-09 | |||
| JP2020134519A | 2020-08-31 | |||
| JPS6048104A | 1985-03-15 | |||
| JPS61209016A | 1986-09-17 | |||
| JP5114471B2 | 2013-01-09 |
Other References:
HIROHISA MIKAMI, YOSHIHIRO HAYAKAWA: "Sample Introduction System in Liquid Chromatograph", CHROMATOGRAPHY, KUROMATOGURAFI KAGAKKAI, JP, vol. 32, no. 1, 1 January 2011 (2011-01-01), JP , pages 17 - 21, XP009542888, ISSN: 1342-8284
HIROHISA MIKAMI: "Sample Introduction Device in Liquid Chromatography", CHROMATOGRAPHY, vol. 32, no. 1, 2011, pages 17 - 21
HIROHISA MIKAMI: "Sample Introduction Device in Liquid Chromatography", CHROMATOGRAPHY, vol. 32, no. 1, 2011, pages 17 - 21
Attorney, Agent or Firm:
KIMURA Masayoshi (JP)
Download PDF: