Title:
LIQUID CRYSTAL NANOPARTICLES, PREPARATION METHOD THEREFOR, DRUG DELIVERY SYSTEM CONTAINING LIPOPHILIC DRUG-INCORPORATED LIQUID CRYSTAL NANOPARTICLES
Document Type and Number:
WIPO Patent Application WO/2016/195338
Kind Code:
A2
Abstract:
The present invention relates to liquid crystal nanoparticles improving the pharmacodynamic characteristics of a lipophilic drug, a preparation method therefor, and a drug delivery system containing the same. According to the present invention, the liquid crystal nanoparticles have excellent long-term storagability, physical properties and shape stability, pharmacodynamic characteristics, such as drug extended release and a high blood plasma concentration, are remarkably improved during the delivery of a lipophilic drug, and a lipophilic drug can be selectively delivered only to the liver, and thus the liquid crystal nanoparticles can be used as an effective drug delivery system. In addition, preparation can be readily carried out with low energy and at low cost, and thus the production cost of the liquid crystal nanoparticles can be lowered and productivity can be improved.
Inventors:
KIM BYEONG MOON (KR)
LEE DONG RYEOL (KR)
PARK JI SU (KR)
BAE II HAK (KR)
LEE DONG RYEOL (KR)
PARK JI SU (KR)
BAE II HAK (KR)
Application Number:
PCT/KR2016/005666
Publication Date:
December 08, 2016
Filing Date:
May 27, 2016
Export Citation:
Assignee:
UNIV SEOUL NAT R & DB FOUND (KR)
International Classes:
A61K47/06; A61K47/08; A61K47/10; C09K19/06
Attorney, Agent or Firm:
LEE, WON-HEE (KR)
이원희 (KR)
이원희 (KR)
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