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Title:
LIQUID PHASE SPHERICAL CARRIER, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/127920
Kind Code:
A1
Abstract:
A liquid phase spherical carrier as represented by formula I, a preparation method therefor and use thereof. R is a functional group, preferably a group having hydroxyl, amino, carboxyl or halogen. The liquid phase synthesis carrier can be used for liquid phase synthesis of polypeptides, the preparation method therefor is simple, and the synthesis efficiency is high.

Inventors:
CHEN, Xinliang (4th Floor, Hybio Medicine Park Office Building High-tech Industrial Park Central District, Nansha, Shenzhen Guangdong 7, 518057, CN)
MI, Pengcheng (4th Floor, Hybio Medicine Park Office Building High-tech Industrial Park Central District, Nansha, Shenzhen Guangdong 7, 518057, CN)
PAN, Junfeng (4th Floor, Hybio Medicine Park Office Building High-tech Industrial Park Central District, Nansha, Shenzhen Guangdong 7, 518057, CN)
YUAN, Jiancheng (4th Floor, Hybio Medicine Park Office Building High-tech Industrial Park Central District, Nansha, Shenzhen Guangdong 7, 518057, CN)
Application Number:
CN2018/079285
Publication Date:
July 04, 2019
Filing Date:
March 16, 2018
Export Citation:
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Assignee:
HYBIO PHARMACEUTICAL CO., LTD. (4th Floor, Hybio Medicine Park Office Building High-tech Industrial Park Central District, Nansha, Shenzhen Guangdong 7, 518057, CN)
International Classes:
C07C43/253; C07C41/16; C07C213/08; C07C217/58; C07K1/02; C07K1/04; C07K1/06; C07K14/815
Foreign References:
CN106083626A2016-11-09
CN102286076A2011-12-21
CN104478995A2015-04-01
Other References:
FEDOROVA, N. E.: "Carboxylic fullerene C60 derivatives: efficient microbicides against herpes simplex virus and cytomegalovirus infections in vitro", MENDELEEV COMMUN, 31 December 2012 (2012-12-31)
BIRKETT, P.R.: "Arylation of [60]fullerene via electrophilic aromatic substitution involving the electrophile C60C16: frontside nucleophilic substi tution of fullerenes", J. CHEM. SOC., PERKIN TRANS., vol. 2, 1 January 1997 (1997-01-01), pages 1121 - 1125, XP003017388
TROSHINA, O.A.: "Chlorofullerene C60C16: a precursor for straightforward preparation of highly water-soluble polycarboxylic fullerene derivatives active against HIV", ORG. BIOMOL. CHEM., vol. 5, no. 17, 18 July 2007 (2007-07-18), pages 2783 - 91, XP055136229
Attorney, Agent or Firm:
BEIJING CHENGHUI LAW FIRM (905 Tower 2, No. 99 Chaoyang North Road Chaoyang District, Beijing 3, 100123, CN)
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