LIVE-ATTENUATED COMPOSITIONS FOR BACTERIAL INFECTIONS

Title:

LIVE-ATTENUATED COMPOSITIONS FOR BACTERIAL INFECTIONS

Document Type and Number:

WIPO Patent Application WO/2010/132764

Kind Code:

A3

Abstract:

The present invention relates to compositions and methods for disease treatment and prevention through administration of a live attenuated composition. In particular, the present invention provides compositions and methods for the treatment and prevention of urinary tract infection by administration of a live attenuated compositions lacking O-antigen ligase activity.

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Inventors:

KLUMPP DAVID (US)
SCHAEFFER ANTHONY (US)
BILLIPS BENJAMIN (US)

Application Number:

PCT/US2010/034892

Publication Date:

February 24, 2011

Filing Date:

May 14, 2010

Export Citation:

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Assignee:

UNIV NORTHWESTERN (US)
KLUMPP DAVID (US)
SCHAEFFER ANTHONY (US)
BILLIPS BENJAMIN (US)

International Classes:

A61K35/22; A61K35/74; A61K35/744; A61K39/395; A61P13/00; A61P37/00

Foreign References:

US20060233829A1	2006-10-19
US5066596A	1991-11-19
US20030124634A1	2003-07-03

Other References:

BENJAMIN K. ET AL., INFECTION AND IMMUNITY, vol. 76, no. 9, September 2008 (2008-09-01), pages 3891 - 3900

Attorney, Agent or Firm:

BOND, Jason, R. (S.C2275 Deming Way,STE 31, Middleton WI, US)

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