Title:
LIVING CELL CULTURE AND REAL-TIME OBSERVATION SYSTEM AND METHOD
Document Type and Number:
WIPO Patent Application WO/2022/036807
Kind Code:
A1
Abstract:
A living cell culture and real-time observation system, relating to the technical fields of cell culture and microscopic imaging. The living cell culture and real-time observation system comprises a cell imaging apparatus. The cell imaging apparatus comprises a cell culture dish (1) for bearing a living cell sample and a culture solution; an image sensor chip (2), which is provided with a photosensitive area (21), wherein the front surface of the image sensor chip (2) is attached to the bottom surface of the cell culture dish (1), and the photosensitive area (21) is completely exposed at the bottom surface of the cell culture dish (1) and is used for recording a projected microscopic image of the living cell sample; and a light source apparatus (3), which is fixed above the image sensor chip (2) and is used for providing a light source for imaging of the living cell sample. The living cell culture and real-time observation system further comprises: a living cell incubator (4) for the cell imaging apparatus to be placed therein and for providing a growth and reproduction environment for the living cell sample; and a control apparatus (5) for controlling the image sensor chip (2) and the light source apparatus (3) and receiving, processing and displaying the projected microscopic image of the living cell sample. By means of the present invention, a large field of view is obtained, the efficiency is improved, phenomena that cannot be observed with a traditional microscope can be observed, and the cost of living cell culture and observation is reduced.
Inventors:
YANG CHENG (CN)
SHEN XINYU (CN)
YAN FENG (CN)
CAO XUEYUN (CN)
LIN LANKUN (CN)
MENG YUNLONG (CN)
SHEN XINYU (CN)
YAN FENG (CN)
CAO XUEYUN (CN)
LIN LANKUN (CN)
MENG YUNLONG (CN)
Application Number:
PCT/CN2020/117859
Publication Date:
February 24, 2022
Filing Date:
September 25, 2020
Export Citation:
Assignee:
NANJING UNIVERSITY OF TECHNOLOGY (CN)
International Classes:
C12M3/00; C12M1/22; C12M1/34; C12M1/36; C12M1/38; G01N21/01
Foreign References:
| CN111607513A | 2020-09-01 | |||
| CN110540940A | 2019-12-06 | |||
| CN106834118A | 2017-06-13 | |||
| US20120142086A1 | 2012-06-07 | |||
| CN208844100U | 2019-05-10 | |||
| CN102864078A | 2013-01-09 | |||
| CN108728333A | 2018-11-02 |
Attorney, Agent or Firm:
SHANGHAI SHENXIN LAW FIRM (CN)
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