Title:
LONG LASTING DRUG FORMULATIONS
Document Type and Number:
WIPO Patent Application WO/2013/069016
Kind Code:
A3
Abstract:
The present invention is directed to long-lasting erythropoietin therapeutic formulations and their methods of use wherein the formulation comprises a genetically modified micro-organ that comprises a vector which comprises a nucleic acid sequence operably linked to one or more regulatory sequences, wherein the nucleic acid sequence encodes erythropoietin.
Inventors:
PEARLMAN ANDREW L (IL)
STERN BARUCH S (IL)
STERN BARUCH S (IL)
Application Number:
PCT/IL2012/050448
Publication Date:
July 18, 2013
Filing Date:
November 08, 2012
Export Citation:
Assignee:
MEDGENICS MEDICAL ISRAEL LTD (IL)
International Classes:
A01N63/00; A61K35/36; A61K48/00
Foreign References:
| US20080090777A1 | 2008-04-17 |
Other References:
MITRANI, E ET AL.: "Biopump: Autologous Skin-Derived Micro-Organ Genetically Engineered To Provide Sustained Continuous Secretion Of Therapeutic Proteins.", DERMATOLOGIC THERAPY., vol. 24, 2011, pages 489 - 497
LIPPIN, Y ET AL.: "Human Erythropoietin Gene Thereapy For Patients With Chronic Renal Failure.", BLOOD., vol. 106, no. 7, 1 October 2005 (2005-10-01), pages 2290 - 2296
LIPPIN, Y ET AL.: "Human Erythropoietin Gene Thereapy For Patients With Chronic Renal Failure.", BLOOD., vol. 106, no. 7, 1 October 2005 (2005-10-01), pages 2290 - 2296
Attorney, Agent or Firm:
PEARL COHEN ZEDEK LATZER et al. (46733 Herzelia, IL)
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