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Title:
LOW-VISCOSITY LIQUID-CRYSTAL COMPOUND
Document Type and Number:
WIPO Patent Application WO/2011/078383
Kind Code:
A1
Abstract:
Provided is a liquid-crystal compound which is usable as a base for injections. The compound is an amphipathic compound represented by general formula (I), wherein X and Y each represents a hydrogen atom or X and Y in cooperation represent an oxygen atom, n is an integer of 0-2, m is 1 or 2, and R represents a hydrophilic group formed by removing one hydroxy group from any compound selected from a group consisting of glycerol, erythritol, pentaerythritol, diglycerol, triglycerol, xylose, sorbitol, ascorbic acid, glucose, galactose, mannose, dipentaerythritol, maltose, mannitol, and xylitol. Also provided are a base for injections and a depot preparation both comprising the amphipathic compound.

Inventors:
IKEDA Yutaka (Inc. 1-8-10, Nihonbashi-Muromachi, Chuo-k, Tokyo 22, 〒1030022, JP)
池田豊 (〒22 東京都中央区日本橋室町1丁目8番10号 株式会社サイトパスファインダー内 Tokyo, 〒1030022, JP)
YAMASHITA Jun (Inc. 1-8-10, Nihonbashi-Muromachi, Chuo-k, Tokyo 22, 〒1030022, JP)
山下隼 (〒22 東京都中央区日本橋室町1丁目8番10号 株式会社サイトパスファインダー内 Tokyo, 〒1030022, JP)
HIJIKURO Ichiro (4-10-2 Nihonbashi-Honcho, Chuo-k, Tokyo 23, 〒1030023, JP)
土黒一郎 (〒23 東京都中央区日本橋本町4-10-2 株式会社ケムジェネシス内 Tokyo, 〒1030023, JP)
Application Number:
JP2010/073621
Publication Date:
June 30, 2011
Filing Date:
December 27, 2010
Export Citation:
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Assignee:
CYTOPATHFINDER, INC. (1-8-10, Nihonbashi-Muromachi Chuo-k, Tokyo 22, 〒1030022, JP)
株式会社サイトパスファインダー (〒22 東京都中央区日本橋室町1丁目8番10号 Tokyo, 〒1030022, JP)
CHEMGENESIS INCORPORATED (4-10-2, Nihonbashi-Honcho Chuo-k, Tokyo 23, 〒1030023, JP)
株式会社ケムジェネシス (〒23 東京都中央区日本橋本町4-10-2 Tokyo, 〒1030023, JP)
IKEDA Yutaka (Inc. 1-8-10, Nihonbashi-Muromachi, Chuo-k, Tokyo 22, 〒1030022, JP)
池田豊 (〒22 東京都中央区日本橋室町1丁目8番10号 株式会社サイトパスファインダー内 Tokyo, 〒1030022, JP)
YAMASHITA Jun (Inc. 1-8-10, Nihonbashi-Muromachi, Chuo-k, Tokyo 22, 〒1030022, JP)
山下隼 (〒22 東京都中央区日本橋室町1丁目8番10号 株式会社サイトパスファインダー内 Tokyo, 〒1030022, JP)
International Classes:
C07C43/178; A61K9/10; A61K47/14; C07C69/30; C07H15/10
Domestic Patent References:
WO2006043705A12006-04-27
WO2009087485A22009-07-16
WO2006043705A12006-04-27
Foreign References:
JPS6028945A1985-02-14
JPS6028946A1985-02-14
JP2002505307A2002-02-19
JP2001231845A2001-08-28
JP2009295658A2009-12-17
Other References:
BARAUSKAS, J. ET AL.: "Phase Behavior of the Phytantriol/Water System", LANGMUIR, vol. 19, no. 23, 2003, pages 9562 - 9565, XP055111491
See also references of EP 2518040A4
LAUGHLIN, R. G.: "The Aqueous Phase Behavior of Surfactants", 1994, ACADEMIC PRESS, pages: 106 - 117
LASIC D. D., TIBTECH, vol. 16, 1998, pages 307 - 321
FONTELL, K., COLLOID & POLYMER SCI., vol. 268, 1990, pages 264 - 285
BARAUSKAS, J.; LANDH, T., LANGMUIR, vol. 19, 2003, pages 9562 - 9565
Attorney, Agent or Firm:
HIRAKI Yusuke et al. (Kamiya-cho MT Bldg. 19F, 3-20 Toranomon 4-chome, Minato-k, Tokyo 01, 〒1050001, JP)
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