Title:
A LOWER TOXICITY AND ANTI-INFLAMMATORY AND ANTI-EXUDATION PHARMACEUTICAL COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2001/049293
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition that is lower toxicity and antiphlogistic as well as anti-exudation. The composition contains escin of general formula (I) and escin of general formula (II) as active components and pharmaceutically acceptable additives. As compared with the total escins, the present pharmaceutical composition has the same level of anti-inflammatory action and anti-exudation, but the toxicity and stimulation are much lower.
Inventors:
LIU WANHUI (CN)
ZHANG QINGCHUN (CN)
LI SHIXU (CN)
SU KAJIA (CN)
LIU SHUYAN (CN)
ZHU FABING (CN)
ZHANG QINGCHUN (CN)
LI SHIXU (CN)
SU KAJIA (CN)
LIU SHUYAN (CN)
ZHU FABING (CN)
Application Number:
PCT/CN1999/000222
Publication Date:
July 12, 2001
Filing Date:
December 30, 1999
Export Citation:
Assignee:
SHANDONG LUYE PHARM CO LTD (CN)
LIU WANHUI (CN)
ZHANG QINGCHUN (CN)
LI SHIXU (CN)
SU KAJIA (CN)
LIU SHUYAN (CN)
ZHU FABING (CN)
LIU WANHUI (CN)
ZHANG QINGCHUN (CN)
LI SHIXU (CN)
SU KAJIA (CN)
LIU SHUYAN (CN)
ZHU FABING (CN)
International Classes:
A61K31/56; A61K31/70; C07J53/00; C07J63/00; (IPC1-7): A61K31/56; C07J53/00; C07J63/00
Foreign References:
| JPH1017591A | 1998-01-20 |
Other References:
BIOL. PHARM. BULL., vol. 20, no. 10, 1997, pages 1092 - 1095
BIOORG. MED. CHEM. LETT, vol. 7, no. 13, 1997, pages 1611 - 1616
J. SMOOTH. MUSCLE. RES., vol. 32, no. 5, 1996, pages 219 - 228
CHEM. PHARM. BULL., vol. 46, no. 11, 1998, pages 1764 - 1769
BIOORG. MED. CHEM. LETT, vol. 7, no. 13, 1997, pages 1611 - 1616
J. SMOOTH. MUSCLE. RES., vol. 32, no. 5, 1996, pages 219 - 228
CHEM. PHARM. BULL., vol. 46, no. 11, 1998, pages 1764 - 1769
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (2 Fuchengmenwai St, Beijing 7, CN)
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