Title:
LU AE58054 HYDROCHLORIDE CRYSTALLINE FORM A, AND PREPARATION METHOD AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/078587
Kind Code:
A1
Abstract:
The present invention relates to Lu AE58054 hydrochloride crystalline form A, and preparation method and application thereof, Lu AE58054 hydrochloride crystalline form A having a characteristic peak at a point where 2theta value is 17.1°±0.2°、17.8°±0.2°、21.4°±0.2° in an X-ray powder diffraction pattern (Cu-Kα radiation) under 25°C. Having a simple preparation process, a low cost, a good stability, a low moisture absorbance property, a high solubility, Crystalline form A is beneficial to absorption of drugs, and has a great significance in reducing drug load and preparing pharmaceutical formulation for curing Alzheimer disease.
Inventors:
CHEN MINHUA (CN)
ZHANG YANFENG (CN)
LIU KAI (CN)
ZHANG XIAOYU (CN)
ZHANG YANFENG (CN)
LIU KAI (CN)
ZHANG XIAOYU (CN)
Application Number:
PCT/CN2015/094921
Publication Date:
May 26, 2016
Filing Date:
November 18, 2015
Export Citation:
Assignee:
CRYSTAL PHARMATECH CO LTD (CN)
International Classes:
C07D209/14; A61K31/4045; A61P25/28
Foreign References:
| CN1610547A | 2005-04-27 | |||
| CN102656146A | 2012-09-05 |
Attorney, Agent or Firm:
BOSS & YOUNG PATENT AND TRADEMARK LAW OFFICE (CN)
北京邦信阳专利商标代理有限公司 (CN)
北京邦信阳专利商标代理有限公司 (CN)
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