Title:
LUNG CANCER MONITORING KIT AND APPLICATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/157831
Kind Code:
A1
Abstract:
A lung cancer monitoring kit and an application method thereof. The monitoring kit comprises: a reagent A prepared by adding 5% of SDS into an ammonium bicarbonate solution having a concentration of 10 mM; a reagent B prepared by adding not less than 2.2 unit/μL of an exoglycosidase into NP40 having a concentration of 3.3%; a reagent C comprising a mixed solution of equal volumes of 20 mM of APTS in 1.2 M of a citric acid and 1 M of an organic reducing agent in DMSO; and a reagent D comprising 0.25 μL NH4AC having a concentration of 100 mM and pH 5, 0.2 μL of a neuraminidase, and 2.55 μL hydrogen peroxide. The kit is used to evaluate a lung cancer patient on the basis of a diagnostic indicator of a fingerprinting pattern generated by detecting oligosaccharide chains in a blood glycoprotein, so as to diagnose a tumor stage of a lung cancer, implementing regular and non-invasive detection for a lung cancer patient, and monitoring the progress of the disease in real time.
Inventors:
CHEN CUIYING (CN)
Application Number:
PCT/CN2018/077713
Publication Date:
September 07, 2018
Filing Date:
March 01, 2018
Export Citation:
Assignee:
JIANGSU XIANSIDA BIOTECHNOLOGY CO LTD (CN)
XIANSIDA NANJING BIOTECHNOLOGY CO LTD (CN)
CHANGZHOU JITAI BIOLOGY TECH CO LTD (CN)
XIANSIDA NANJING BIOTECHNOLOGY CO LTD (CN)
CHANGZHOU JITAI BIOLOGY TECH CO LTD (CN)
International Classes:
G01N33/574
Domestic Patent References:
WO2013096455A1 | 2013-06-27 |
Foreign References:
CN106950379A | 2017-07-14 | |||
CN107505295A | 2017-12-22 | |||
CN106950380A | 2017-07-14 | |||
CN102565318A | 2012-07-11 | |||
CN1449496A | 2003-10-15 | |||
CN103969371A | 2014-08-06 |
Attorney, Agent or Firm:
JW IP LAW FIRM (CN)
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