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Title:
LUNG CANCER MONITORING KIT AND APPLICATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/157831
Kind Code:
A1
Abstract:
A lung cancer monitoring kit and an application method thereof. The monitoring kit comprises: a reagent A prepared by adding 5% of SDS into an ammonium bicarbonate solution having a concentration of 10 mM; a reagent B prepared by adding not less than 2.2 unit/μL of an exoglycosidase into NP40 having a concentration of 3.3%; a reagent C comprising a mixed solution of equal volumes of 20 mM of APTS in 1.2 M of a citric acid and 1 M of an organic reducing agent in DMSO; and a reagent D comprising 0.25 μL NH4AC having a concentration of 100 mM and pH 5, 0.2 μL of a neuraminidase, and 2.55 μL hydrogen peroxide. The kit is used to evaluate a lung cancer patient on the basis of a diagnostic indicator of a fingerprinting pattern generated by detecting oligosaccharide chains in a blood glycoprotein, so as to diagnose a tumor stage of a lung cancer, implementing regular and non-invasive detection for a lung cancer patient, and monitoring the progress of the disease in real time.

Inventors:
CHEN CUIYING (CN)
Application Number:
PCT/CN2018/077713
Publication Date:
September 07, 2018
Filing Date:
March 01, 2018
Export Citation:
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Assignee:
JIANGSU XIANSIDA BIOTECHNOLOGY CO LTD (CN)
XIANSIDA NANJING BIOTECHNOLOGY CO LTD (CN)
CHANGZHOU JITAI BIOLOGY TECH CO LTD (CN)
International Classes:
G01N33/574
Domestic Patent References:
WO2013096455A12013-06-27
Foreign References:
CN106950379A2017-07-14
CN107505295A2017-12-22
CN106950380A2017-07-14
CN102565318A2012-07-11
CN1449496A2003-10-15
CN103969371A2014-08-06
Attorney, Agent or Firm:
JW IP LAW FIRM (CN)
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