Title:
LUTERIAL AND METHOD FOR ISOLATING AND CULTURING SAME
Document Type and Number:
WIPO Patent Application WO/2015/108246
Kind Code:
A1
Abstract:
The present invention relates to blood-derived luterial and a method for isolating and culturing the same. The luterial according to the present invention is a cell or cell analogue which (1) is present in blood, semen, serous fluid, saliva, and cytosol; (2) exhibits a positive chromogenic reaction for Janus green B, Acridine orange, and Rhodamine 123 in the immunofluorescence test; (3) exhibits expression characteristics of genes derived from beta-proteobacteria and gamma-proteobacteria at the optimum condition (pH 7.2-7.4) and has a size of 30-800 nm; (4) exhibits expression characteristics of genes derived from eukaryotic cells as well as genes derived from beta-proteobacteria and gamma-proteobacteria in the acidified condition, the Sterptophyta genes being mainly expressed, the size being increased to from 400 nm or more to 2000 nm or more; (5) is involved in ATP production at the normal condition, and (6) is different from mitochondria, is completely different from exosome, and has fusion characteristics of a middle stage between prokaryotic cells and eukaryotic cells.
Inventors:
CHOI WON CHEOL (KR)
KWON YOUNG AH (KR)
KWON SUNG PIL (KR)
JUN HYUN JUNG (US)
KWON YOUNG AH (KR)
KWON SUNG PIL (KR)
JUN HYUN JUNG (US)
Application Number:
PCT/KR2014/004197
Publication Date:
July 23, 2015
Filing Date:
May 09, 2014
Export Citation:
Assignee:
CHOI WON CHEOL (KR)
KWON YOUNG AH (KR)
KWON YOUNG AH (KR)
International Classes:
C12Q1/24; C12N1/00
Domestic Patent References:
| WO2011127219A1 | 2011-10-13 |
Foreign References:
| KR20060094211A | 2006-08-29 | |||
| KR20130056855A | 2013-05-30 | |||
| US20130337440A1 | 2013-12-19 | |||
| US20130203081A1 | 2013-08-08 | |||
| KR20130082060A | 2013-07-12 |
Other References:
LEE ET AL.: "Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy", HUMAN MOLECULAR GENETICS, vol. 21, no. ISSUE, 2012, pages R125 - R134, XP055094171
THROMB.HAEMOST, vol. 82, 1999, pages 794
J.BOIL.CHEM., vol. 274, 1999, pages 7545
J.BIOL.CHEM., vol. 276, 2001, pages 19672
CARDIOVASC.RES, vol. 49, no. 5, 2001, pages 88
See also references of EP 3095875A4
THROMB.HAEMOST, vol. 82, 1999, pages 794
J.BOIL.CHEM., vol. 274, 1999, pages 7545
J.BIOL.CHEM., vol. 276, 2001, pages 19672
CARDIOVASC.RES, vol. 49, no. 5, 2001, pages 88
See also references of EP 3095875A4
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
이처영 (KR)
이처영 (KR)
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