Title:
METHOD FOR TESTING FOR IgG4-RELATED DISEASE
Document Type and Number:
WIPO Patent Application WO/2018/016607
Kind Code:
A1
Abstract:
The present invention addresses the problem of finding a pathogenic substance causing an IgG4-related disease and providing a method for testing for an IgG4-related disease and others using the pathogenic substance. The present invention provides a method for testing for an IgG4-related disease, said method comprising an anti-laminin antibody detection step of detecting, as an indicator for an IgG4-related disease, an antibody capable of immunologically reacting with laminin in a sample and/or an anti-integrin antibody detection step of detecting, as an indicator for an IgG4-related disease, an antibody capable of immunologically reacting with integrin in the sample. The present invention also provides: a test reagent for use in the testing for an IgG4-related disease, which contains laminin; and a test reagent for use in the testing for an IgG4-related disease, which contains integrin.
Inventors:
SHIOKAWA MASAHIRO (JP)
KODAMA YUZO (JP)
CHIBA TSUTOMU (JP)
KODAMA YUZO (JP)
CHIBA TSUTOMU (JP)
Application Number:
PCT/JP2017/026359
Publication Date:
January 25, 2018
Filing Date:
July 20, 2017
Export Citation:
Assignee:
UNIV KYOTO (JP)
International Classes:
G01N33/53; G01N33/15; G01N33/50; C07K16/18
Domestic Patent References:
| WO2015123565A1 | 2015-08-20 | |||
| WO2002042769A1 | 2002-05-30 | |||
| WO2015013508A2 | 2015-01-29 |
Foreign References:
| JP2012050369A | 2012-03-15 | |||
| JP2002514660A | 2002-05-21 |
Other References:
SHIOKAWA, M ET AL.: "Pathogenicity of IgG in patients with IgG4-related disease", GUT, vol. 65, no. 8, 10 March 2016 (2016-03-10), pages 1322 - 1332, DOI: 10.2958/suizo.33.743
SHIOKAWA, M ET AL.: "Risk of cancer in patients with autoimmune pancreatitis", THE AMERICAN JOURNAL OF GASTROENTEROLOGY, vol. 108, April 2013 (2013-04-01), pages 610 - 617, DOI: 10.1038/ajg.2012.465
KAWANO MITSHUIRO ET AL: "IgG4-related kidney disease. Diagnosis and treatment", JAPANESE JOURNAL OF CLINICAL IMUNOLOGY, vol. 38, no. 1, 1 January 2015 (2015-01-01), pages 8 - 16, XP055602463
SHIOKAWA, M ET AL.: "Risk of cancer in patients with autoimmune pancreatitis", THE AMERICAN JOURNAL OF GASTROENTEROLOGY, vol. 108, April 2013 (2013-04-01), pages 610 - 617, DOI: 10.1038/ajg.2012.465
KAWANO MITSHUIRO ET AL: "IgG4-related kidney disease. Diagnosis and treatment", JAPANESE JOURNAL OF CLINICAL IMUNOLOGY, vol. 38, no. 1, 1 January 2015 (2015-01-01), pages 8 - 16, XP055602463
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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