Title:
METHODS OF DETECTING Lp-PLA2 ACTIVITY
Document Type and Number:
WIPO Patent Application WO2005074604
Kind Code:
A3
Abstract:
This invention relates to a method for measuring enzymatically active Lipoproteinassociated Phospholipase A2 (Lp-PLA2) in a sample. Further, this invention relates to a Hybrid Immunocapture method for measuring enzymatically active Lp-PLA2 in a sample. Specifically, this invention relates to a Hybrid Immunocapture method for measuring enzymatically active Lp-PLA2 in a sample utilizing an enzymatically active Lp-PLA2 standard. In addition, this invention relates to a kit for measuring enzymatically active LpPLA2 in a sample. Specifically, this invention relates to a kit for measuring enzymatically active Lp-PLA2 in a sample containing an enzymatically active Lp-PLA2 standard.
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Inventors:
WOLFERT ROBERT L (US)
KIM NAM (US)
DUAN XIAOZHU (US)
KIM NAM (US)
DUAN XIAOZHU (US)
Application Number:
PCT/US2005/003211
Publication Date:
December 29, 2005
Filing Date:
February 03, 2005
Export Citation:
Assignee:
DIADEXUS INC (US)
WOLFERT ROBERT L (US)
KIM NAM (US)
DUAN XIAOZHU (US)
WOLFERT ROBERT L (US)
KIM NAM (US)
DUAN XIAOZHU (US)
International Classes:
C07D271/08; C07K16/00; C12Q1/44; G01N33/53; G01N33/573; (IPC1-7): G01N33/53; G01N33/573; C07K16/00
Foreign References:
US20020177209A1 | 2002-11-28 |
Other References:
KUJIRAOKA ET AL: "Altered distribution of plasma PAF-AH between HDLs and other lipoproteins in hyperlipidemia and diabetes mellitus.", JOURNAL OF LIPID RESEARCH., vol. 44, 2003, pages 2006 - 2014, XP008092123
KOSAKA ET AL: "Spectrophotometric assay for serum platelet-activating factor acetylhydrolase activity.", CLINICA CHIMICA ACTA., vol. 296, 2000, pages 151 - 161, XP002997443
KOSAKA ET AL: "Spectrophotometric assay for serum platelet-activating factor acetylhydrolase activity.", CLINICA CHIMICA ACTA., vol. 296, 2000, pages 151 - 161, XP002997443
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