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Title:
MACROCYCLIC COMPOUNDS AND COMPOSITIONS USEFUL AS BACE INHIBITORS
Document Type and Number:
WIPO Patent Application WO2006074940
Kind Code:
A3
Abstract:
The invention relates to novel macrocyclic compounds of the formula in which R1, R3, V1, V2, X1, X2, Y, Z, Ar, AA and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16, 17 or 18, in free base form or in acid addition salt form, to their preparation, to their use as medicaments and to medicaments comprising them.

Inventors:
LERCHNER ANDREAS (CH)
MACHAUER RAINER (DE)
SIMIC OLIVER (DE)
TINTELNOT-BLOMLEY MARINA (DE)
Application Number:
EP2006000265W
Publication Date:
August 31, 2006
Filing Date:
January 13, 2006
Export Citation:
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Assignee:
NOVARTIS AG
NOVARTIS PHARMA GMBH
LERCHNER, ANDREAS
MACHAUER, RAINER
SIMIC, OLIVER
TINTELNOT-BLOMLEY, MARINA
International Classes:
C07D245/06; A61K31/395; A61P25/28; C07D273/02; C07D281/00; C07D291/08; C07D413/04; C07D413/12; C07D419/12
Domestic Patent References:
WO2002100856A12002-12-19
WO2002100399A12002-12-19
WO2005049585A12005-06-02
WO2005003106A12005-01-13
WO2006014944A12006-02-09
WO2005016876A22005-02-24
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