MACROCYCLIC COMPOUNDS AND COMPOSITIONS USEFUL AS BACE INHIBITORS

Title:

MACROCYCLIC COMPOUNDS AND COMPOSITIONS USEFUL AS BACE INHIBITORS

Document Type and Number:

WIPO Patent Application WO2006074940

Kind Code:

A3

Abstract:

The invention relates to novel macrocyclic compounds of the formula in which R₁, R₃, V₁, V₂, X₁, X₂, Y, Z, Ar, AA and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16, 17 or 18, in free base form or in acid addition salt form, to their preparation, to their use as medicaments and to medicaments comprising them.

More Like This:

WO/1994/022440

BICYCLIC COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION

Inventors:

LERCHNER ANDREAS (CH)
MACHAUER RAINER (DE)
SIMIC OLIVER (DE)
TINTELNOT-BLOMLEY MARINA (DE)

Application Number:

PCT/EP2006/000265

Publication Date:

August 31, 2006

Filing Date:

January 13, 2006

Export Citation:

Click for automatic bibliography generation Help

Assignee:

NOVARTIS AG (CH)
NOVARTIS PHARMA GMBH (AT)
LERCHNER ANDREAS (CH)
MACHAUER RAINER (DE)
SIMIC OLIVER (DE)
TINTELNOT-BLOMLEY MARINA (DE)

International Classes:

C07D245/06; A61K31/395; A61P25/28; C07D273/02; C07D281/00; C07D291/08; C07D413/04; C07D413/12; C07D419/12

Domestic Patent References:

WO2002100856A1	2002-12-19
WO2002100399A1	2002-12-19
WO2005049585A1	2005-06-02
WO2005003106A1	2005-01-13
WO2006014944A1	2006-02-09
WO2005016876A2	2005-02-24

Download PDF:

View/Download PDF PDF Help

Previous Patent: DEVICE AND METHOD FOR PREPARING HOT CHOCOLATE MILK

Next Patent: POLYMER MATERIAL SHOWING A SHARP DEPENDENCY OF TENSILE STRENGTH IN RELATION TO TWO EXTERNAL STIMULI