Title:
MACROCYCLIC QUINAZOLE DERIVATIVES AND THEIR USE AS MTKI
Document Type and Number:
WIPO Patent Application WO2006061417
Kind Code:
A3
Abstract:
The present invention concerns kinase inhibitors formula, formula (I), the N-oxide forms, the pharmaceutically isomeric forms thereof, wherein Z represents NH and the other substituents are defined as in the claims.
Inventors:
FREYNE EDDY JEAN EDGARD (BE)
WILLEMS MARC (BE)
TEN HOLTE PETER (BE)
PAPANIKOS ALEXANDRA (BE)
EMBRECHTS WERNER CONSTANT JOHA (BE)
STORCK PIERRE HENRI (FR)
PONCELET VIRGINIE SOPHIE (FR)
WILLEMS MARC (BE)
TEN HOLTE PETER (BE)
PAPANIKOS ALEXANDRA (BE)
EMBRECHTS WERNER CONSTANT JOHA (BE)
STORCK PIERRE HENRI (FR)
PONCELET VIRGINIE SOPHIE (FR)
Application Number:
PCT/EP2005/056609
Publication Date:
August 03, 2006
Filing Date:
December 08, 2005
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NV (BE)
FREYNE EDDY JEAN EDGARD (BE)
WILLEMS MARC (BE)
TEN HOLTE PETER (BE)
PAPANIKOS ALEXANDRA (BE)
EMBRECHTS WERNER CONSTANT JOHA (BE)
STORCK PIERRE HENRI (FR)
PONCELET VIRGINIE SOPHIE (FR)
FREYNE EDDY JEAN EDGARD (BE)
WILLEMS MARC (BE)
TEN HOLTE PETER (BE)
PAPANIKOS ALEXANDRA (BE)
EMBRECHTS WERNER CONSTANT JOHA (BE)
STORCK PIERRE HENRI (FR)
PONCELET VIRGINIE SOPHIE (FR)
International Classes:
C07D498/08; A61K31/529; A61P35/00; C07D239/00; C07D273/00
Domestic Patent References:
| WO2004105765A1 | 2004-12-09 | |||
| WO1996033980A1 | 1996-10-31 | |||
| WO1996013529A1 | 1996-05-09 |
Foreign References:
| US6344459B1 | 2002-02-05 |
Other References:
"4-ANILINOQUINAZOLINE DERIVATIVES", EXPERT OPINION ON THERAPEUTIC PATENTS, ASHLEY PUBLICATIONS, GB, vol. 8, no. 4, 1998, pages 475 - 478, XP000999463, ISSN: 1354-3776
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