Title:
MACROLIDE COMPOUND HAVING ANTICANCER EFFECT
Document Type and Number:
WIPO Patent Application WO/2012/086114
Kind Code:
A1
Abstract:
The present invention relates to a macrolide compound expected to inhibit cell proliferation, as well as to a novel anticancer agent using the same. Specifically, the present invention relates to a compound represented by Formula (I) or (II), or a pharmacologically acceptable salt thereof, as well as to a cell proliferation inhibitor having the same as an active ingredient, and to an anticancer agent.
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Inventors:
FUWA HARUHIKO (JP)
SASAKI MAKOTO (JP)
KUBO HIROSHI (JP)
SUZUKI TAKAYA (JP)
SASAKI MAKOTO (JP)
KUBO HIROSHI (JP)
SUZUKI TAKAYA (JP)
Application Number:
PCT/JP2011/006057
Publication Date:
June 28, 2012
Filing Date:
October 28, 2011
Export Citation:
Assignee:
UNIV TOHOKU (JP)
FUWA HARUHIKO (JP)
SASAKI MAKOTO (JP)
KUBO HIROSHI (JP)
SUZUKI TAKAYA (JP)
FUWA HARUHIKO (JP)
SASAKI MAKOTO (JP)
KUBO HIROSHI (JP)
SUZUKI TAKAYA (JP)
International Classes:
C07D493/18; A61K31/365; A61P35/00; A61P35/02
Domestic Patent References:
| WO1996040869A1 | 1996-12-19 |
Other References:
COOK, C. ET AL.: "Total Synthesis of (-)- Exiguolide", ORGANIC LETTERS, vol. 12, no. 4, February 2010 (2010-02-01), pages 744 - 747, XP055111035
FUWA, H. ET AL.: "Total Synthesis of (-)- Exiguolide", ORGANIC LETTERS, vol. 12, no. 3, February 2010 (2010-02-01), pages 584 - 587, XP055111038
See also references of EP 2657238A4
FUWA, H. ET AL.: "Total Synthesis of (-)- Exiguolide", ORGANIC LETTERS, vol. 12, no. 3, February 2010 (2010-02-01), pages 584 - 587, XP055111038
See also references of EP 2657238A4
Attorney, Agent or Firm:
OHNO, Seiji et al. (JP)
Seiji Ono (JP)
Seiji Ono (JP)
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Claims: