Title:
MAGNETIC CELL SEPARATION
Document Type and Number:
WIPO Patent Application WO/2008/133726
Kind Code:
A3
Abstract:
Systems and methods are provided separating a first group of cells from a mixture of at least first and second groups of cells in a suspending fluid. The system includes an annular flow channel and at least one magnetic element positioned around the exterior of the annular flow channel as to provide a radially symmetric magnetic field around at least a portion of the annular flow channel. The at least one magnetic element is configured to provide a gradually increasing magnetic field along the axis of flow as to limit the maximum magnetic gradient within the annular flow channel. A pump is operatively connected to a terminal end of the annular flow channel to force the suspending fluid through the annular channel.
Inventors:
CHALMERS JEFFREY J (US)
LARA-VELASCO OSCAR R (US)
TONG XIAODONG (US)
ZBOROWSKI MACIEJ (US)
MOORE LEE R (US)
FARAG SHERIF S (US)
LARA-VELASCO OSCAR R (US)
TONG XIAODONG (US)
ZBOROWSKI MACIEJ (US)
MOORE LEE R (US)
FARAG SHERIF S (US)
Application Number:
PCT/US2007/084685
Publication Date:
January 20, 2011
Filing Date:
November 14, 2007
Export Citation:
Assignee:
CLEVELAND CLINIC FOUNDATION (US)
UNIV OHIO STATE (US)
CHALMERS JEFFREY J (US)
LARA-VELASCO OSCAR R (US)
TONG XIAODONG (US)
ZBOROWSKI MACIEJ (US)
MOORE LEE R (US)
FARAG SHERIF S (US)
UNIV OHIO STATE (US)
CHALMERS JEFFREY J (US)
LARA-VELASCO OSCAR R (US)
TONG XIAODONG (US)
ZBOROWSKI MACIEJ (US)
MOORE LEE R (US)
FARAG SHERIF S (US)
International Classes:
B03C1/28
Domestic Patent References:
| WO2004078316A1 | 2004-09-16 |
Foreign References:
| US6346196B1 | 2002-02-12 | |||
| US6129848A | 2000-10-10 | |||
| DE102004040785A1 | 2006-03-02 | |||
| US20050155921A1 | 2005-07-21 |
Attorney, Agent or Firm:
WESORICK, Richard, S. (Sundheim Covell & Tummino L.L.P.,1300 East Ninth Street, Suite 170, Cleveland OH, US)
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