Title:
MAGNETIC RESONANCE IMAGING DEVICE AND METHOD FOR CALCULATING OXYGEN EXTRACTION FRACTIONS
Document Type and Number:
WIPO Patent Application WO/2018/083952
Kind Code:
A1
Abstract:
Provided is technology to calculate oxygen extraction fraction distribution in a brain containing cerebral parenchyma using simple processing without applying a load such as caffeine administration to a patient when calculating the oxygen extraction fraction distribution using MRI. This MRI device for this purpose measures a complex image of a nuclear magnetic resonance signal and, from the measured complex image, calculates a physical property value distribution for calculating a physical property value image that reflects the oxygen extraction fraction. The calculated physical property value distribution is separated into at least two types of physical property value distributions (tissue separation images) for each tissue. After converting any of the tissue separation images into an oxygen extraction fraction, the oxygen extraction fraction distribution is estimated on the basis of the condition that the pixel value of an arbitrary pixel and the average value of pixels surrounding the pixel are substantially equal.
Inventors:
SHIRAI TORU (JP)
SATOH RYOTA (JP)
TANIGUCHI YO (JP)
OCHI HISAAKI (JP)
SOTOME YOSHIHISA (JP)
BITO YOSHITAKA (JP)
MURASE TAKENORI (JP)
SATOH RYOTA (JP)
TANIGUCHI YO (JP)
OCHI HISAAKI (JP)
SOTOME YOSHIHISA (JP)
BITO YOSHITAKA (JP)
MURASE TAKENORI (JP)
Application Number:
PCT/JP2017/036826
Publication Date:
May 11, 2018
Filing Date:
October 11, 2017
Export Citation:
Assignee:
HITACHI LTD (JP)
International Classes:
A61B5/055; G06T1/00; G01N24/08
Foreign References:
| JP2015062637A | 2015-04-09 |
Other References:
BOLAR, D. S. ET AL.: "Imagine of Oxygenation", PROC. INTL. SOC. MAG. RESON. MED. 23 (ISMRM15), 2015, pages 1 - 11, XP055503301, Retrieved from the Internet
ZHANG, J. ET AL.: "High Resolution Cerebral Metabolic Rate of Oxygen [CMRO2] using Quantitative Susceptibility Mapping (QSM) and an Oxygen Extractioi Fraction (OEF) Constraint", PROC. INTL. SOC. MAG. RESON. MED. 23 (ISMRM15), 2015
DIMOV, A. ET AL.: "Estimation of Blood Oxygenation using Quantitative Susceptibility Mapping, ISMRM, 23", INSTITUTE OF NAVIGATION, 2015
MCDANIEL, P. ET AL.: "Improved Accuracy in Susceptibility-based OEF Measurements by Mitigation of Partial-Volume Effects via Combined Magnitude and Phase Reconstruction", PROC. INTL. SOC. MAG. RESON. MED. 23 (ISMRM 23RD), 2015
ZHANG, J. ET AL.: "High Resolution Cerebral Metabolic Rate of Oxygen [CMRO2] using Quantitative Susceptibility Mapping (QSM) and an Oxygen Extractioi Fraction (OEF) Constraint", PROC. INTL. SOC. MAG. RESON. MED. 23 (ISMRM15), 2015
DIMOV, A. ET AL.: "Estimation of Blood Oxygenation using Quantitative Susceptibility Mapping, ISMRM, 23", INSTITUTE OF NAVIGATION, 2015
MCDANIEL, P. ET AL.: "Improved Accuracy in Susceptibility-based OEF Measurements by Mitigation of Partial-Volume Effects via Combined Magnitude and Phase Reconstruction", PROC. INTL. SOC. MAG. RESON. MED. 23 (ISMRM 23RD), 2015
Attorney, Agent or Firm:
SANNOZAKA PATENT LAW FIRM (JP)
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