Title:
MAMMALIAN GENES INVOLVED IN INFECTION
Document Type and Number:
WIPO Patent Application WO/2011/146527
Kind Code:
A3
Abstract:
The present invention relates to cellular proteins that are involved in infection or are otherwise associated with the life cycle of one or more pathogens.
Inventors:
RUBIN DONALD (US)
MURRAY JAMES (US)
HODGE THOMAS (US)
MURRAY JAMES (US)
HODGE THOMAS (US)
Application Number:
PCT/US2011/036873
Publication Date:
August 02, 2012
Filing Date:
May 17, 2011
Export Citation:
Assignee:
ZIRUS INC (US)
RUBIN DONALD (US)
MURRAY JAMES (US)
HODGE THOMAS (US)
UNIV VANDERBILT (US)
RUBIN DONALD (US)
MURRAY JAMES (US)
HODGE THOMAS (US)
UNIV VANDERBILT (US)
International Classes:
A61K39/395; A61K38/16; A61K38/17; A61P31/12; C12N15/12; G01N33/15
Other References:
KOBONG CHOI ET AL.: "Identification of cellular proteins enhancing activities of internal ribosomal entry sites by competition with oligodeoxynucleotides", NUCLEIC ACIDS RESEARCH, vol. 32, no. 4, 2004, pages 1308 - 1317
ANDREA V. GAMARNIK ET AL.: "'Two functional complexes formed by KH domain containing proteins with the 5' noncoding region of poliovirus RNA'", RNA, vol. 3, no. 8, 1997, pages 882 - 892, XP009130844
BRIAN COLLIER ET AL.: "Translational inhibition in vitro of human papillomavirus type 16 L2 mRNA mediated through interaction with heterogenous ribonucleoprotein K and poly(rC)-binding proteins 1 and 2", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 273, no. 35, 1998, pages 22648 - 22656
TONG ZHANG ET AL.: "PCBP-1 regulates alternative splicing of the CD44 gene and inhibits invasion in human hepatoma cell line HepG2 cells", MOLECULAR CANCER, vol. 9, no. 72, April 2010 (2010-04-01), XP021078043, ISSN: 1476-4598, Retrieved from the Internet DOI: doi:10.1186/1476-4598-9-72
M. R. PILLAI ET AL.: "Expression of folate receptors and heterogeneous nuclear ribonucleoprotein E1 in women with human papillomavirus mediated transformation of cervical tissue to cancer", J. CLIN. PATHOL., vol. 56, no. 8, 2003, pages 569 - 574, XP009130830
ANDREA V. GAMARNIK ET AL.: "'Two functional complexes formed by KH domain containing proteins with the 5' noncoding region of poliovirus RNA'", RNA, vol. 3, no. 8, 1997, pages 882 - 892, XP009130844
BRIAN COLLIER ET AL.: "Translational inhibition in vitro of human papillomavirus type 16 L2 mRNA mediated through interaction with heterogenous ribonucleoprotein K and poly(rC)-binding proteins 1 and 2", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 273, no. 35, 1998, pages 22648 - 22656
TONG ZHANG ET AL.: "PCBP-1 regulates alternative splicing of the CD44 gene and inhibits invasion in human hepatoma cell line HepG2 cells", MOLECULAR CANCER, vol. 9, no. 72, April 2010 (2010-04-01), XP021078043, ISSN: 1476-4598, Retrieved from the Internet
M. R. PILLAI ET AL.: "Expression of folate receptors and heterogeneous nuclear ribonucleoprotein E1 in women with human papillomavirus mediated transformation of cervical tissue to cancer", J. CLIN. PATHOL., vol. 56, no. 8, 2003, pages 569 - 574, XP009130830
Attorney, Agent or Firm:
CLEVELAND, Janell, T. (Inc.1384 Buford Business Blvd NE,Suite 70, Buford GA, US)
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