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Title:
MANGANESE PEROXIDASE, GENE THEREOF, AND USE THEREOF IN DETOXIFICATION OF MYCOTOXIN
Document Type and Number:
WIPO Patent Application WO/2018/218476
Kind Code:
A1
Abstract:
The present invention provides use of a manganese peroxidase in the detoxification of mycotoxins, and specifically, the present invention provides five manganese peroxidases (MnP-1, MnP-2, MnP-4, MnP-5, and MnP-6), genes thereof, and uses thereof. The present invention provides five manganese peroxidases (MnP-1, MnP-2, MnP-4, MnP-5, and MnP-6) derived from lignocellulose degradation bacteria, the amino acid sequences thereof being as set forth in SEQ ID NO: 1, SEQ ID NO: 4, SEQ ID NO: 7, SEQ ID NO: 10, and SEQ ID NO: 13.

Inventors:
YAO BIN (CN)
SU XIAOYUN (CN)
QIN HUANG (CN)
LUO HUIYING (CN)
HUANG HUOQING (CN)
BAI YINGGUO (CN)
WANG YUAN (CN)
WANG YARU (CN)
MA RUI (CN)
TU TAO (CN)
MA JIANSHUANG (CN)
Application Number:
PCT/CN2017/086534
Publication Date:
December 06, 2018
Filing Date:
May 31, 2017
Export Citation:
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Assignee:
FEED RES INSTITUTE OF CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CN)
International Classes:
C12N9/08; C12N15/53; C12N15/70
Foreign References:
CN107012131A2017-08-04
CN104232555A2014-12-24
Other References:
WANG, JIANQIAO ET AL.: "Detoxification of Aflatoxin B1 by Manganese Peroxidase from the White-rot Fungus Phanerochaete Sordida YK-624", FEMS MICROBIOLOGY LETTERS, vol. 314, no. 2, 31 January 2011 (2011-01-31), XP055554285
YEHIA, R.S.: "Aflatoxin Detoxification by Manganese Peroxidase Purified from Pleurotus Ostreatus", BRAZILIAN JOURNAL OF MICROBIOLOGY, vol. 45, no. 1, 1 May 2014 (2014-05-01), XP055554286
DATABASE Protein 9 June 2012 (2012-06-09), YU , CUN ET AL.: "manganese peroxidase 1 [Cerrena unicolor]", XP055554294, retrieved from NCBI Database accession no. AFK91528.1
SAMBROOK ET AL.: "Molecular Cloning: A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY, COLD SPRING HARBOR LABORATORY PRESS
See also references of EP 3674401A4
Attorney, Agent or Firm:
BEIJING HUA LONG DRAGON PATENT AGENCY (GENERAL PARTNERSHIP) (CN)
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