Title:
α-MANGOSTIN DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/114501
Kind Code:
A1
Abstract:
The present invention provides an α-mangostin derivative having a structure of general formula I, a preparation method thereof, and an application of the same in preparing a drug for treating a brain injury caused by ischemia, such as vascular dementia and cerebral infarction. The vascular dementia is learning and memory impairment induced by a vascular disease or brain ischemia or cell loss in the dentate gyrus of the hippocampus.
Inventors:
ZHAN ZHAJUN (CN)
SHAN WEIGUANG (CN)
CHEN YAN (CN)
WANG JIANWEI (CN)
MA LIEFENG (CN)
SHAN WEIGUANG (CN)
CHEN YAN (CN)
WANG JIANWEI (CN)
MA LIEFENG (CN)
Application Number:
PCT/CN2018/116330
Publication Date:
June 20, 2019
Filing Date:
November 20, 2018
Export Citation:
Assignee:
UNIV ZHEJIANG TECHNOLOGY (CN)
International Classes:
C07D311/86; A61K31/352; A61P25/28
Domestic Patent References:
| WO2015127512A1 | 2015-09-03 |
Foreign References:
| US20070015820A1 | 2007-01-18 | |||
| CN106554341A | 2017-04-05 | |||
| CN101270110A | 2008-09-24 | |||
| CN105218507A | 2016-01-06 |
Attorney, Agent or Firm:
HANGZHOU TIANQIN INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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