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Title:
MANUFACTURING METHOD AND MANUFACTURING INTERMEDIATE FOR DIPHENYLSULFIDE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2015/194157
Kind Code:
A1
Abstract:
[Problem] To provide a technique relating to a novel manufacturing method for a diphenylsulfide derivative. [Solution] An optical resolution method for subjecting a compound represented by general formula (6) to optical resolution using an optical resolution column and collecting a separated compound represented by general formula (7) and/or a compound represented by general formula (8). Also, a compound manufacturing method comprising said optical resolution method.

Inventors:
GOTO, Takayuki (KYORIN PHARMACEUTICAL CO. LTD., 1848, Nogi, Nogi-machi, Shimotsuga-gu, Tochigi 14, 〒3290114, JP)
SATO, Masanori (KYORIN PHARMACEUTICAL CO. LTD., 1848, Nogi, Nogi-machi, Shimotsuga-gu, Tochigi 14, 〒3290114, JP)
USHIWATA, Makoto (KYORIN PHARMACEUTICAL CO. LTD., 1848, Nogi, Nogi-machi, Shimotsuga-gu, Tochigi 14, 〒3290114, JP)
ABE, Yasunori (KYORIN PHARMACEUTICAL CO. LTD., 1848, Nogi, Nogi-machi, Shimotsuga-gu, Tochigi 14, 〒3290114, JP)
SAKAMOTO, Nobutaka (KYORIN PHARMACEUTICAL CO. LTD., 1848, Nogi, Nogi-machi, Shimotsuga-gu, Tochigi 14, 〒3290114, JP)
MIYOSHI, Keita (KYORIN PHARMACEUTICAL CO. LTD., 1848, Nogi, Nogi-machi, Shimotsuga-gu, Tochigi 14, 〒3290114, JP)
Application Number:
JP2015/002985
Publication Date:
December 23, 2015
Filing Date:
June 15, 2015
Export Citation:
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Assignee:
KYORIN PHARMACEUTICAL CO., LTD. (6 Kanda Surugadai 4-chome, Chiyoda-ku Tokyo, 11, 〒1018311, JP)
International Classes:
C07C319/28; C07C319/20; C07C323/32; C07C323/63; C07F9/09; C07B57/00; C07B61/00
Domestic Patent References:
WO2011004604A12011-01-13
WO2008018427A12008-02-14
WO2012086184A12012-06-28
WO2009099174A12009-08-13
Other References:
CHINO,M. ET AL.: "An efficient total synthesis of a sphingosine-1-phosphate receptor agonist KRP- 203", TETRAHEDRON, vol. 64, no. 17, 2008, pages 3859 - 3866, XP022520419
Attorney, Agent or Firm:
MIZUNO, Katsufumi et al. (721 Marunouchi-Nakadori Bldg, 2-3 Marunouchi 2-chome, Chiyoda-k, Tokyo 05, 〒1000005, JP)
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