Title:
MANUFACTURING METHOD FOR TABLET
Document Type and Number:
WIPO Patent Application WO/2012/153383
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a manufacturing method for a tablet which uses citric acid, maintains the tablet-shape thereof even when conveyed, does not generate carbon dioxide gas when stored, and completely dissolves in water when used. The solution to this problem is a manufacturing method wherein a granulated substance (A) obtained, using a mechanical fluidized-bed granulator which is not substantially used for air agitation, by raising the temperature of a powder which is a mixture of citric acid and polyethylene glycol to 60-65°C and then cooling, and a granulated substance (B) obtained, using a mechanical fluidized-bed granulator which is not substantially used for air agitation, by raising the temperature of a powder which is a mixture of sodium hydrogencarbonate and polyethylene glycol to 60-65°C and then cooling, are mixed in a manner such that the ratio of the second granulated substance (B) relative to the first granulated substance (A) is 1:2-1:10, and then the mixture is compression molded into a tablet.
Inventors:
KOBOSHI SHIGEHARU (JP)
YOSHIMOTO HIROSHI (JP)
YOSHIMOTO HIROSHI (JP)
Application Number:
PCT/JP2011/060696
Publication Date:
November 15, 2012
Filing Date:
May 10, 2011
Export Citation:
Assignee:
HOT ALBUM TANSANSEN TABLET INC (JP)
KOBOSHI SHIGEHARU (JP)
YOSHIMOTO HIROSHI (JP)
KOBOSHI SHIGEHARU (JP)
YOSHIMOTO HIROSHI (JP)
International Classes:
C09K3/00; A61K8/19; A61K8/365; A61K8/86; A61Q19/10
Domestic Patent References:
| WO2001052820A1 | 2001-07-26 |
Foreign References:
| JP2002275051A | 2002-09-25 | |||
| JPS61176519A | 1986-08-08 | |||
| JP2011021004A | 2011-02-03 | |||
| JP2011105615A | 2011-06-02 |
Attorney, Agent or Firm:
SAKAGUCHI Nobuaki (JP)
Nobuaki Sakaguchi (JP)
Nobuaki Sakaguchi (JP)
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Claims:
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