Title:
MARKER FOR IDENTIFYING GERM CELLS HAVING ENGRAFTABILITY AT HOST GONAD
Document Type and Number:
WIPO Patent Application WO/2017/164391
Kind Code:
A1
Abstract:
The present invention relates to a marker for identifying germ cells, comprising (I) a marker for identifying germ cells having engraftability at a host gonad and/or (II) a marker for identifying germ cells not having engraftability at a host gonad. The present invention provides a germ cell marker that can identify the presence or absence of engraftability at a host gonad in fish.
Inventors:
HAYASHI MAKOTO (JP)
IWASAKI YOSHIKO (JP)
HAYASHI TETSUTARO (JP)
EBISAWA MASASHI (JP)
SASAGAWA YOHEI (JP)
YOSHIMURA MIKA (JP)
NIKAIDO ITOSHI (JP)
ICHIDA KENSUKE (JP)
YOSHIZAKI GORO (JP)
IWASAKI YOSHIKO (JP)
HAYASHI TETSUTARO (JP)
EBISAWA MASASHI (JP)
SASAGAWA YOHEI (JP)
YOSHIMURA MIKA (JP)
NIKAIDO ITOSHI (JP)
ICHIDA KENSUKE (JP)
YOSHIZAKI GORO (JP)
Application Number:
PCT/JP2017/012112
Publication Date:
September 28, 2017
Filing Date:
March 24, 2017
Export Citation:
Assignee:
NAT UNIV CORP TOKYO UNIV OF MARINE SCIENCE AND TECH (JP)
UNIV TSUKUBA (JP)
UNIV TSUKUBA (JP)
International Classes:
C12N15/09; C07K16/18; C12N5/075; C12Q1/68
Domestic Patent References:
| WO2009118778A1 | 2009-10-01 | |||
| WO2016042684A1 | 2016-03-24 |
Other References:
DATABASE Nucleotide [online] 11 September 2006 (2006-09-11), "CR373234 AGENAE Rainbow trout normalized testis library (tcbi) Oncorhynchus mykiss cDNA clone tcbi0029. e. 11 5", XP055601953, retrieved from NCBI Database accession no. CR373234.2
DATABASE NUCLEOTIODE [online] 24 August 2010 (2010-08-24), "Salmo salar clone ssal-eve-547-353 Microfibrillar-associated protein 2 precursor putative mRNA", XP055601960, retrieved from NCBI Database accession no. BT056416.1
DATABASE GenBank [online] 24 August 2010 (2010-08-24), "Salmo salar clone ssal-rgb2-555-140 Thyroliberin type A precursor putative mRNA", XP055601963, Database accession no. BT048522.1
DATABASE Nucleotide [online] 24 August 2010 (2010-08-24), "Salmo salar clone ssal-eve-507-163 Tubulin beta-2C chain putative mRNA", XP055601977, retrieved from NCBI Database accession no. BT056899.1
DATABASE Nucleotide [online] 29 December 2006 (2006-12-29), "1284580 NCCCWA 03RT Oncorhynchus mykiss cDNA clone 03RT117M12 3", XP055601982, retrieved from NCBI Database accession no. CX144839.1
DATABASE Nucleotide [online] 20 November 2008 (2008-11-20), "EST_omyk_evn_814168 omykevn RBC Oncorhynchus mykiss cDNA Oncorhynchus mykiss cDNA clone omyk_evn_508_376 5", XP055601986, Database accession no. GE826476.1
DATABASE GenBank [online] 21 December 2012 (2012-12-21), "TSA: Oncorhynchus mykiss mRNA, contig: YGL02. 4929. C1", XP055601988, Database accession no. FX355071.1
HAYASHI, M. ET AL.: "Enrichment of spermatogonial stem cells using side population in teleost", BIOL. REPROD., vol. 91, no. 1, 2014, pages 1 - 8, XP055562657, DOI: doi:10.1095/biolreprod.113.114140
YAZAWA, R. ET AL.: "The Pacific Bluefin Tuna (Thunnus orientalis) dead end gene is suitable as a specific molecular marker of type A spermatogonia", MOL. REPROD. DEV., vol. 80, 2013, pages 871 - 880, XP055602008
SALEM, M. ET AL.: "Characterization of the rainbow trout transcriptome using Sanger and 454-pyrosequencingapproaches", BMC GENOMICS, vol. 11, 2010, pages 564, XP021072861, DOI: doi:10.1186/1471-2164-11-564
DATABASE NUCLEOTIODE [online] 24 August 2010 (2010-08-24), "Salmo salar clone ssal-eve-547-353 Microfibrillar-associated protein 2 precursor putative mRNA", XP055601960, retrieved from NCBI Database accession no. BT056416.1
DATABASE GenBank [online] 24 August 2010 (2010-08-24), "Salmo salar clone ssal-rgb2-555-140 Thyroliberin type A precursor putative mRNA", XP055601963, Database accession no. BT048522.1
DATABASE Nucleotide [online] 24 August 2010 (2010-08-24), "Salmo salar clone ssal-eve-507-163 Tubulin beta-2C chain putative mRNA", XP055601977, retrieved from NCBI Database accession no. BT056899.1
DATABASE Nucleotide [online] 29 December 2006 (2006-12-29), "1284580 NCCCWA 03RT Oncorhynchus mykiss cDNA clone 03RT117M12 3", XP055601982, retrieved from NCBI Database accession no. CX144839.1
DATABASE Nucleotide [online] 20 November 2008 (2008-11-20), "EST_omyk_evn_814168 omykevn RBC Oncorhynchus mykiss cDNA Oncorhynchus mykiss cDNA clone omyk_evn_508_376 5", XP055601986, Database accession no. GE826476.1
DATABASE GenBank [online] 21 December 2012 (2012-12-21), "TSA: Oncorhynchus mykiss mRNA, contig: YGL02. 4929. C1", XP055601988, Database accession no. FX355071.1
HAYASHI, M. ET AL.: "Enrichment of spermatogonial stem cells using side population in teleost", BIOL. REPROD., vol. 91, no. 1, 2014, pages 1 - 8, XP055562657, DOI: doi:10.1095/biolreprod.113.114140
YAZAWA, R. ET AL.: "The Pacific Bluefin Tuna (Thunnus orientalis) dead end gene is suitable as a specific molecular marker of type A spermatogonia", MOL. REPROD. DEV., vol. 80, 2013, pages 871 - 880, XP055602008
SALEM, M. ET AL.: "Characterization of the rainbow trout transcriptome using Sanger and 454-pyrosequencingapproaches", BMC GENOMICS, vol. 11, 2010, pages 564, XP021072861, DOI: doi:10.1186/1471-2164-11-564
Attorney, Agent or Firm:
NAGAI Hiroshi et al. (JP)
Download PDF:
Previous Patent: ANTIBODY CAPABLE OF BINDING TO UNDIFFERENTIATED GERM CELLS OF SCOMBRIDAE FISH
Next Patent: SHIP
Next Patent: SHIP