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Patent Searching and Data


Title:
MARKER FOR MULTIPLE SCLEROSIS
Document Type and Number:
WIPO Patent Application WO/2019/163838
Kind Code:
A1
Abstract:
The present invention provides a method for testing for multiple sclerosis, the method comprising a step for measuring secretory receptor-type protein tyrosine phosphatase Z (PTPRZ) in a sample obtained from a subject. When the measurement value of the secretory PTPRZ level in the sample obtained from the subject is lower in comparison with the PTPRZ levels in samples of a control group, it is indicated that the subject is affected with multiple sclerosis. Said secretory PTPRZ is either secretory PTPRZ isoform 1 or secretory PTPRZ isoform 2, or both.

Inventors:
KITAZUME, Shinobu (1 Hikarigaoka, Fukushima-sh, Fukushima 95, 〒9601295, JP)
SAKUDA, Kanoko (2-1 Hirosawa, Wako-sh, Saitama 98, 〒3510198, JP)
TANIGUCHI, Naoyuki (2-1 Hirosawa, Wako-sh, Saitama 98, 〒3510198, JP)
HASHIMOTO, Yasuhiro (1 Hikarigaoka, Fukushima-sh, Fukushima 95, 〒9601295, JP)
HONDA, Takashi (1 Hikarigaoka, Fukushima-sh, Fukushima 95, 〒9601295, JP)
SAITO, Kiyoshi (1 Hikarigaoka, Fukushima-sh, Fukushima 95, 〒9601295, JP)
FUJII, Masazumi (1 Hikarigaoka, Fukushima-sh, Fukushima 95, 〒9601295, JP)
Application Number:
JP2019/006365
Publication Date:
August 29, 2019
Filing Date:
February 20, 2019
Export Citation:
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Assignee:
RIKEN (2-1 Hirosawa, Wako-shi Saitama, 98, 〒3510198, JP)
FUKUSHIMA MEDICAL UNIVERSITY (1 Hikarigaoka, Fukushima-shi Fukushima, 95, 〒9601295, JP)
International Classes:
G01N33/68; C12Q1/42; G01N33/53
Attorney, Agent or Firm:
TAKASHIMA, Hajime (Meiji Yasuda Seimei Osaka Midosuji Bldg, 1-1 Fushimimachi 4-chome, Chuo-ku, Osaka-sh, Osaka 44, 〒5410044, JP)
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