MARKER FOR PREDICTING PRESSURE ULCER DEVELOPMENT AND USE THEREOF

Title:

MARKER FOR PREDICTING PRESSURE ULCER DEVELOPMENT AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2017/122780

Kind Code:

A1

Abstract:

A marker for predicting pressure ulcer development, selected from the group consisting of interleukin (IL)-1α, vascular endothelial growth factor (VEGF)-C, plasminogen activator inhibitor (PAI)-1, and heat shock protein (HSP) 90α.

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Inventors:

SANADA HIROMI (JP)
NAKAGAMI GOJIRO (JP)
MINEMATSU TAKEO (JP)

Application Number:

PCT/JP2017/001020

Publication Date:

July 20, 2017

Filing Date:

January 13, 2017

Export Citation:

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Assignee:

UNIV TOKYO (JP)

International Classes:

G01N33/53; C12N15/09; C12Q1/68

Other References:

KANEKO, M. ET AL.: "Compression-induced HIF-1 enhances thrombosis and PAI-1 expression in mouse skin", WOUND REPAIR AND REGENERATION, vol. 23, no. 5, September 2015 (2015-09-01), pages 657 - 663, XP055399538
SISCO, M. ET AL.: "Reduced up-regulation of cytoprotective genes in rat cutaneous tissue during the second cycle of ischemia-reperfusion", WOUND REPAIR AND REGENERATION, vol. 15, no. 2, March 2007 (2007-03-01), pages 203 - 212, XP003026831
NORIKO HORI ET AL.: "Skin Blotting-ho o Mochiita Taiatsu Bunsan Mattress no Jokuso Yobo Koka no Hyoka", JAPANESE JOURNAL OF PRESSURE ULCERS, vol. 16, no. 3, August 2014 (2014-08-01), pages 361
KONYA, C. ET AL.: "Change of cytokine in pressure ulcer with undermining", JOURNAL OF THE TSURUMA HEALTH SCIENCE SOCIETY, vol. 28, no. 1, December 2004 (2004-12-01), pages 25 - 30
TOMOYUKI KUROSE ET AL.: "Rat Jokuso Jikken Model ni yoru Hatsugen Idenshi no Kaiseki", ACTA ANATOMICA NIPPONICA, pages 224