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Title:
MARKER SEQUENCES FOR DIAGNOSING PROSTATE CANCER, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2012/107596
Kind Code:
A3
Abstract:
The invention relates to novel marker sequences for prostate cancer, excluding inflammatory prostate diseases, diabetes, or polymorbidity, and the diagnostic use thereof, including a method for screening potential agents for such prostate diseases by means of said marker sequences. The invention further relates to a diagnostic device containing such marker sequences for prostate cancer, in particular a protein biochip and the use thereof.

Inventors:
LUEKING ANGELIKA (DE)
KOWALD AXEL (DE)
BARTSCH GEORG (AT)
KLOCKER HELMUT (AT)
Application Number:
PCT/EP2012/052438
Publication Date:
March 28, 2013
Filing Date:
February 13, 2012
Export Citation:
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Assignee:
PROTAGEN AG (DE)
LUEKING ANGELIKA (DE)
KOWALD AXEL (DE)
BARTSCH GEORG (AT)
KLOCKER HELMUT (AT)
International Classes:
C12Q1/68
Domestic Patent References:
WO2009080017A22009-07-02
WO2010081240A12010-07-22
WO2010000874A22010-01-07
WO2003091695A22003-11-06
Foreign References:
US20070161023A12007-07-12
US20060280748A12006-12-14
US20040259086A12004-12-23
US20060088894A12006-04-27
US20090298184A12009-12-03
US20100216654A12010-08-26
US20040038321A12004-02-26
US20020187518A12002-12-12
Other References:
DATABASE Genbank [online] NCBI; 26 December 2010 (2010-12-26), HEINZEN, E.L., YOON, W., TATE, S.K., SEN, A., WOOD, N.W., SISODIYA, S.M., GOLDSTEIN, D.B.: "Homo sapiens neuro-oncological ventral antigen 2 (NOVA2), mRNA.", XP002661368, Database accession no. NM_002516
PORKKA K P ET AL: "DETECTION OF DIFFERENTIALLY EXPRESSED GENES IN PROSTATE CANCER BY COMBINING SUPRESSION SUBTRACTIVE HYBRIDIZATION AND CDNA LIBRARY ARRAY", JOURNAL OF PATHOLOGY, JOHN WILEY & SONS LTD, GB, vol. 193, no. 1, 1 January 2001 (2001-01-01), pages 73 - 79, XP008010824, ISSN: 0022-3417
WEIZMANN INSTITUTE OF SCIENCE: "GeneAnnot for the Gene Symbols HBXAP (a.k.a. RSF1), DYRK2, YY1, C19orf12 for HG-U95, HG-U133 and HG-U133 Plus 2.0", INTERNET CITATION, 21 April 2011 (2011-04-21), pages 1 - 4, XP002661374, Retrieved from the Internet [retrieved on 20110421]
WELLMANN AXEL ET AL: "Analysis of microdissected prostate tissue with ProteinChip(R) arrays: A wayto new insights into carcinogenesis and to diagnostic tools", INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, SPANDIDOS PUBLICATIONS, GR, vol. 9, no. 4, 1 April 2002 (2002-04-01), pages 341 - 347, XP009091922, ISSN: 1107-3756
Attorney, Agent or Firm:
SIMANDI, Claus (Höhenstrasse 26, Hennef, DE)
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