Title:
MASS SPECTROMETER AND SPECTROMETRY, WHICH USE NEAR INFRARED FLUORESCENCE
Document Type and Number:
WIPO Patent Application WO/2017/171176
Kind Code:
A1
Abstract:
A mass spectrometer using near infrared (NIR) fluorescence can comprise: a plate formed such that a sample, which includes a matrix for ionization and a fluorescent material having an excitation wavelength of an NIR wavelength band, is loaded thereon; a fluorescence detection unit formed so as to acquire a fluorescence image by using the fluorescent material from the sample on the plate; a light emission unit formed so as to emit a laser beam for ionization at the sample on the plate; and an ion detection unit formed so as to detect, by using the laser beam, ions generated from the sample. By using the NIR fluorescence, fluorescence interference due to a matrix used for MALDI imaging can be excluded even after coating the matrix, and since fluorescence interference due to auto-fluorescence inside tissue is low, fluorescence can be measured even for a thick sample, and thus accurate analysis can be performed by performing MALDI imaging on a more important part, of a sample, which is determined on the basis of a fluorescence image.
Inventors:
OH JOOYEON (KR)
KIM YANG SUN (KR)
KIM YANG SUN (KR)
Application Number:
PCT/KR2016/012234
Publication Date:
October 05, 2017
Filing Date:
October 28, 2016
Export Citation:
Assignee:
ASTA CO LTD (KR)
International Classes:
G01N21/64; G01N21/359; G01N27/62; H01J49/26
Foreign References:
| KR20030077554A | 2003-10-01 | |||
| JPH10142155A | 1998-05-29 | |||
| JP2001091464A | 2001-04-06 | |||
| KR20030078612A | 2003-10-08 | |||
| JPH06221923A | 1994-08-12 |
Other References:
See also references of EP 3438648A4
Attorney, Agent or Firm:
KIM, Sun-young (KR)
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