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Title:
MASS SPECTROMETER AND SPECTROMETRY, WHICH USE NEAR INFRARED FLUORESCENCE
Document Type and Number:
WIPO Patent Application WO/2017/171176
Kind Code:
A1
Abstract:
A mass spectrometer using near infrared (NIR) fluorescence can comprise: a plate formed such that a sample, which includes a matrix for ionization and a fluorescent material having an excitation wavelength of an NIR wavelength band, is loaded thereon; a fluorescence detection unit formed so as to acquire a fluorescence image by using the fluorescent material from the sample on the plate; a light emission unit formed so as to emit a laser beam for ionization at the sample on the plate; and an ion detection unit formed so as to detect, by using the laser beam, ions generated from the sample. By using the NIR fluorescence, fluorescence interference due to a matrix used for MALDI imaging can be excluded even after coating the matrix, and since fluorescence interference due to auto-fluorescence inside tissue is low, fluorescence can be measured even for a thick sample, and thus accurate analysis can be performed by performing MALDI imaging on a more important part, of a sample, which is determined on the basis of a fluorescence image.

Inventors:
OH, Jooyeon (#905, 120-13, Jungang-ro 29-gil,,Yangcheon-gu, Seoul, 08057, KR)
KIM, Yang Sun (#1-301, 19, Geumgok-ro 7beon-gil,,Bundang-gu, Seongnam-si, Gyeonggi-do, 13632, KR)
Application Number:
KR2016/012234
Publication Date:
October 05, 2017
Filing Date:
October 28, 2016
Export Citation:
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Assignee:
ASTA CO., LTD. (11F, 145, Gwanggyo-ro,,Yeongtong-gu, Suwon-si, Gyeonggi-do, 16229, KR)
International Classes:
G01N21/64; G01N21/359; G01N27/62; H01J49/26
Foreign References:
KR20030077554A2003-10-01
JPH10142155A1998-05-29
JP2001091464A2001-04-06
KR20030078612A2003-10-08
JPH06221923A1994-08-12
Attorney, Agent or Firm:
KIM, Sun-young (Korea Coal Center, 10th Floor,58, Jongno 5-gil,,Jongno-gu, Seoul, 03151, KR)
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