Title:
MATERIAL FOR IMPROVING ENDOMETRIOSIS AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2018/159632
Kind Code:
A1
Abstract:
[Problem] To provide a material for improving endometriosis with which it is possible to improve endometriosis and which is a material in which aglycone isoflavones are utilized, and a method for producing the material. [Solution] Production of a material for improving endometriosis, the material having aglycone isoflavones provided with an effect for improving endometriosis, and containing aglycone isoflavones that have beans as the raw material by: inoculating beans with koji mold to produce koji; adding water to the product of this koji-production treatment, thereby hydrolyzing the protein in the product and decomposing the glycosides of the isoflavone compounds in the beans; and producing isoflavone compounds that include a large amount of aglycone.
Inventors:
AMAMI TOMOHIRO (JP)
SHIGEHIRO SOICHIRO (JP)
KITAWAKI JO (JP)
TAKAOKA OSAMU (JP)
SHIGEHIRO SOICHIRO (JP)
KITAWAKI JO (JP)
TAKAOKA OSAMU (JP)
Application Number:
PCT/JP2018/007328
Publication Date:
September 07, 2018
Filing Date:
February 27, 2018
Export Citation:
Assignee:
NICHIMO KK (JP)
KYOTO PREFECTURAL PUBLIC UNIV CORP (JP)
KYOTO PREFECTURAL PUBLIC UNIV CORP (JP)
International Classes:
A61K31/352; A61K36/48; A61P15/00; A61P43/00
Foreign References:
| JP3014145B2 | 2000-02-28 | |||
| JP2002507568A | 2002-03-12 | |||
| JP2009023919A | 2009-02-05 |
Other References:
TAKAOKA,O. ET AL.: "Daidzein-rich isoflavone aglycones inhibit proliferation of human endometriotic stromal cells and in a mouse endometriosis model", 69TH JSOG, vol. 69, no. 2, 23 February 2017 (2017-02-23), pages 520
TAKAOKA, TSUKASA ET AL: "Daidzeinrich isoflavone aglycone restricts proliferation of endometriosis interstitial cells, and prevents cyst formation of endometriosis mouse model - Effect of isoflavone supplement on endometriosis control", ABSTRACTS OF CONFERECNE OF JAPAN SOCIETY FOR DIETRARY SUPPLEMENT, September 2017 (2017-09-01), pages 53
AMAMI, TOMOHIRO: "The beneficial effect of soy isoflavones-aglycone for earlypregnancy", FOOD STYLE 21, vol. 18, no. 6, 2014, pages 65 - 68
TAKAOKA, TSUKASA ET AL: "Daidzeinrich isoflavone aglycone restricts proliferation of endometriosis interstitial cells, and prevents cyst formation of endometriosis mouse model - Effect of isoflavone supplement on endometriosis control", ABSTRACTS OF CONFERECNE OF JAPAN SOCIETY FOR DIETRARY SUPPLEMENT, September 2017 (2017-09-01), pages 53
AMAMI, TOMOHIRO: "The beneficial effect of soy isoflavones-aglycone for earlypregnancy", FOOD STYLE 21, vol. 18, no. 6, 2014, pages 65 - 68
Attorney, Agent or Firm:
NAKAO Shunsuke et al. (JP)
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