Title:
MEANS AND METHODS FOR ASSESSING LIVER DISORDERS
Document Type and Number:
WIPO Patent Application WO/2013/132467
Kind Code:
A3
Abstract:
The present invention pertains to the field of diagnostics for liver disorders and toxicological assessments for risk stratification of chemical compounds. Specifically, it relates to a method for diagnosing liver disorders. It also relates to a method for determining whether a compound is capable of inducing such liver disorders in a subject and to a method of identifying a drug for treating liver disorders. Furthermore, the present invention relates to a device and a kit for diagnosing liver disorders.
Inventors:
WALK TILMANN B (DE)
RAVENZWAAY BENNARD VAN (DE)
MELLERT WERNER (DE)
FABIAN ERIC (DE)
STRAUSS VOLKER (DE)
KAMP HENNICKE (DE)
WIEMER JAN C (DE)
LOOSER RALF (DE)
HEROLD MICHAEL MANFRED (DE)
PROKOUDINE ALEXANDRE (DE)
RAVENZWAAY BENNARD VAN (DE)
MELLERT WERNER (DE)
FABIAN ERIC (DE)
STRAUSS VOLKER (DE)
KAMP HENNICKE (DE)
WIEMER JAN C (DE)
LOOSER RALF (DE)
HEROLD MICHAEL MANFRED (DE)
PROKOUDINE ALEXANDRE (DE)
Application Number:
PCT/IB2013/051862
Publication Date:
October 31, 2013
Filing Date:
March 08, 2013
Export Citation:
Assignee:
BASF SE (DE)
BASF CHINA CO LTD (CN)
BASF CHINA CO LTD (CN)
International Classes:
A61B5/00; A61B19/00
Other References:
JOHN, C. L. ET AL.: "Metabonomics and its role in drug development and disease diagnosis", EXPERT REV. MOL. DIAGN., vol. 4, no. 2, 2004, pages 189 - 199, XP008173374
THIERRY, P ET AL.: "The diagnostic value of bimmarkers(SteatoTest) for the prediction of liver steatosis.", COMPARATIVE HEPATOLOGY, vol. 4, no. 10, 23 December 2005 (2005-12-23), XP021008456
WU, YB. ET AL.: "Duo Zhong Sheng Hua Zhi Biao Lian He Jian Ce Zai Gan Bing Zhen Duan Zhong De Ying Yong.", J MED. THEOR. & PRAC., vol. 23, no. 3, March 2010 (2010-03-01), pages 327 - 328, XP008173439
See also references of EP 2822455A4
THIERRY, P ET AL.: "The diagnostic value of bimmarkers(SteatoTest) for the prediction of liver steatosis.", COMPARATIVE HEPATOLOGY, vol. 4, no. 10, 23 December 2005 (2005-12-23), XP021008456
WU, YB. ET AL.: "Duo Zhong Sheng Hua Zhi Biao Lian He Jian Ce Zai Gan Bing Zhen Duan Zhong De Ying Yong.", J MED. THEOR. & PRAC., vol. 23, no. 3, March 2010 (2010-03-01), pages 327 - 328, XP008173439
See also references of EP 2822455A4
Attorney, Agent or Firm:
DICK, Alexander (PatentanwälteDudenstrasse 46, Mannheim, DE)
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