Title:
MEASUREMENT OF GLYCATED HEMOGLOBIN
Document Type and Number:
WIPO Patent Application WO1999022242
Kind Code:
A3
Abstract:
The invention features a novel method of assaying glycated hemoglobin (GHb) in a sample using a capture molecule e.g. haptoglobin that binds GHb and hemoglobin (Hb), and detecting bound GHb with a molecule that distinguishes GHb from non-glycated hemoglobin (Hb). The molecule used to distinguish GHb from Hb may be an antibody. The assay and antibodies of the invention are useful for the evaluation of GHb in disease states such as diabetes.
Inventors:
ITO RALPH K
SANGHERA GORDON
SANGHERA GORDON
Application Number:
PCT/US1998/021494
Publication Date:
October 07, 1999
Filing Date:
October 09, 1998
Export Citation:
Assignee:
ABBOTT LAB (US)
International Classes:
G01N33/68; G01N33/72; (IPC1-7): G01N33/72; C07K16/44
Domestic Patent References:
| WO1992008984A1 | 1992-05-29 |
Foreign References:
| EP0864865A2 | 1998-09-16 | |||
| EP0573972A2 | 1993-12-15 | |||
| US4861728A | 1989-08-29 | |||
| US4806468A | 1989-02-21 | |||
| US4695552A | 1987-09-22 | |||
| US4438204A | 1984-03-20 | |||
| US4268270A | 1981-05-19 |
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