Title:
MEDICAL PRODUCTS FOR USE IN CONDITIONS RELATED TO MICROBIAL INFECTIONS IN THE UPPER AERODIGESTIVE TRACT
Document Type and Number:
WIPO Patent Application WO/2012/143608
Kind Code:
A3
Abstract:
The present invention concerns products, such as compositions or medical devices, comprising one or more compounds of the Formula I, containing one or more free sulphhydryl groups, where R1 is hydrogen or an acetyl group, and R2 is asulphhydryl groupor a C1-C5 straight chained or branched hydrocarbon chain, optionally containing one or more heteroatoms selected from O, N and S, further containing one or more free sulphhydryl groups, for use in connection with Helicobacter pylori infections or other related infections, either as such or as combinations with antibiotics, whereby the compound(s) and optionally, when present, the antibiotic(s),are mixed with one or more pharmaceutically acceptable carriers providing sustained local release in the stomachor elsewhere in the upper aerodigestive tract.
Inventors:
HAERKOENEN MATTI (FI)
MARVOLA TUULI (FI)
SALASPURO MIKKO (FI)
SUOVANIEMI OSMO (FI)
MARVOLA TUULI (FI)
SALASPURO MIKKO (FI)
SUOVANIEMI OSMO (FI)
Application Number:
PCT/FI2012/050377
Publication Date:
December 13, 2012
Filing Date:
April 18, 2012
Export Citation:
Assignee:
BIOHIT OYJ (FI)
HAERKOENEN MATTI (FI)
MARVOLA TUULI (FI)
SALASPURO MIKKO (FI)
SUOVANIEMI OSMO ANTERO (FI)
HAERKOENEN MATTI (FI)
MARVOLA TUULI (FI)
SALASPURO MIKKO (FI)
SUOVANIEMI OSMO ANTERO (FI)
International Classes:
A61K31/197; A61K9/22; A61P1/04; A61P31/04; A61K47/36
Domestic Patent References:
| WO2005014014A1 | 2005-02-17 | |||
| WO2001089534A1 | 2001-11-29 | |||
| WO2007135242A1 | 2007-11-29 | |||
| WO2011037411A2 | 2011-03-31 |
Other References:
HUYNH, H.Q. ET AL.: "N-Acetylcysteine, a Novel Treatment for Helicobacter pylori Infection.", DIGESTIVE DISEASES AND SCIENCES., vol. 49, 2004, pages 1853 - 1861, XP019237027
ZALA, G. ET AL.: "Omeprazol/Amoxicillin: verbesserte Eradikation von Helicobacter pylori bei Rauchern durch N-Acetylcystein.", SCHWEIZ MED WOCHENSCHR., vol. 124, 1994, pages 1391 - 1397, XP008107454
ZALA, G. ET AL.: "Omeprazol/Amoxicillin: verbesserte Eradikation von Helicobacter pylori bei Rauchern durch N-Acetylcystein.", SCHWEIZ MED WOCHENSCHR., vol. 124, 1994, pages 1391 - 1397, XP008107454
Attorney, Agent or Firm:
SEPPO LAINE OY (Helsinki, FI)
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