Title:
MEDICAL USES OF CD38 AGONISTS
Document Type and Number:
WIPO Patent Application WO/2015/009726
Kind Code:
A3
Abstract:
Methods and compositions relating to medical (e.g., therapeutic) use of CD38 agonists are provided. In some embodiments, the present invention provides methods and compositions relating to use of CD38 in the treatment of cancer, particularly to enhance the efficacy of antibody therapy directed to cancer cells.
Inventors:
GOLDSTEIN MATTHEW J (US)
LEVY RONALD (US)
KOHRT HOLBROOK (US)
LEVY RONALD (US)
KOHRT HOLBROOK (US)
Application Number:
PCT/US2014/046705
Publication Date:
April 02, 2015
Filing Date:
July 15, 2014
Export Citation:
Assignee:
UNIV LELAND STANFORD JUNIOR (US)
International Classes:
A61K39/395; A61K39/00
Foreign References:
| US7223397B1 | 2007-05-29 | |||
| US20120321646A1 | 2012-12-20 |
Other References:
MEHTA, KAPIL ET AL.: "Retinoic acid-induced CD 38 antigen as a target for immunotoxin-mediated killing of leukemia cells.", MOLECULAR CANCER THERAPEUTICS, vol. 3.3, 2004, pages 345 - 352, XP055308462
Attorney, Agent or Firm:
SHERWOOD, Pamela J. (Field & Francis LLP1900 University Avenue, Suite 20, East Palo Alto California, US)
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