Title:
MEDICAMENT FOR TREATING FATTY LIVER AND TREATMENT METHOD
Document Type and Number:
WIPO Patent Application WO/2018/188551
Kind Code:
A1
Abstract:
Uses of an HCBP6 gene or HCBP6 protein as a medicament target in screening and/or preparing a medicament for preventing and/or treating fatty liver, steatohepatitis, diabetes, multiple sclerosis, hypertriglyceridemia, hypercholesterolemia, and/or cardiovascular and cerebral atherosclerosis; uses of an HCBP6 agonist in preparing a medicament for preventing and/or treating fatty liver, steatohepatitis, diabetes, multiple sclerosis, hypertriglyceridemia, hypercholesterolemia, and/or cardiovascular and cerebral atherosclerosis; uses of a ginsenoside in preparing a medicament for preventing and/or treating fatty liver, steatohepatitis, diabetes, multiple sclerosis, hypertriglyceridemia, hypercholesterolemia, and/or cardiovascular and cerebral atherosclerosis; and, an HCBP6 gene-knockout animal model and a preparation method therefor.
Inventors:
CHENG JUN (CN)
Application Number:
PCT/CN2018/082308
Publication Date:
October 18, 2018
Filing Date:
April 09, 2018
Export Citation:
Assignee:
CHENG JUN (CN)
International Classes:
A61K31/575; A61K31/58; A61P3/06; A61P3/10; A61P9/10; C12N15/113; C12N15/873
Foreign References:
| CN103520179A | 2014-01-22 | |||
| CN101507729A | 2009-08-19 |
Other References:
LILI GAO: "HCBP6 Modulates Triglyceride Homeostasis in Hepatocytes Via the SREBP1c/FASN Pathway", JOURNAL OF CELLULAR BIOCHEMISTRY, vol. 116, no. 10, 8 April 2015 (2015-04-08), pages 2375 - 2384, XP055613676, ISSN: 1097-4644
BO, QITAO: "Study on Separation and Activity of Anti-diabetes and lipid regulation of ginsenoside Rb3.", CHINESE MASTER'S THESES, MEDICAL AND HEALTH SCIENCES, no. 11, 15 November 2011 (2011-11-15), pages 36
TINA FLĂYEL: "Genes Affecting beta - Cell Function in Type 1 Diabetes", CURRENT DIABETES REPORTS, vol. 15, no. 97, 21 September 2015 (2015-09-21), pages 1 - 11, XP055613680, ISSN: 1534-4827
BO, QITAO: "Study on Separation and Activity of Anti-diabetes and lipid regulation of ginsenoside Rb3.", CHINESE MASTER'S THESES, MEDICAL AND HEALTH SCIENCES, no. 11, 15 November 2011 (2011-11-15), pages 36
TINA FLĂYEL: "Genes Affecting beta - Cell Function in Type 1 Diabetes", CURRENT DIABETES REPORTS, vol. 15, no. 97, 21 September 2015 (2015-09-21), pages 1 - 11, XP055613680, ISSN: 1534-4827
Attorney, Agent or Firm:
BEIJING CHENGHUI LAW FIRM (CN)
Download PDF:
Previous Patent: PLASTIC MOTOR FOR HANDHELD STABILIZER
Next Patent: FILLING OPENING COVER MECHANISM OF ENERGY BOX AND VEHICLE COMPRISING SAME
Next Patent: FILLING OPENING COVER MECHANISM OF ENERGY BOX AND VEHICLE COMPRISING SAME